Table 5

Standardised variables from the EUROCAT database

	EDMP variables used (core variables are shaded in blue)
Baby and mother
1	CENTRE	Centre number
2	NUMLOC	Local ID of case
3	BIRTH_DATE	Date of birth
4	SEX	Sex
5	NBRBABY	Number of babies delivered
6	SP_TWIN	Specify twin type of birth, like or unlike, zygosity
7	NBRMALF	Number of malformed in multiple set
8	TYPE	Type of birth
9	CIVREG	Civil registration status
10	WEIGHT	Birth weight
11	GESTLENGTH	Length of gestation in completed weeks
12	SURVIVAL	Survival beyond 1 week of age
13	DEATH_DATE	Date of death
14	DATEMO	Date of birth of mother
15	AGEMO	Age of mother at delivery
16	BMI	Maternal body mass index
17	RESIDMO	Mother’s residence code
Diagnosis
19	WHENDISC	When discovered
20	CONDISC	Condition at discovery
21	AGEDISC	If prenatally diagnosed, gestational age at discovery
22	FIRST PRE	First positive prenatal test
24	KARYO	Karyotype of infant/fetus
25	SP_KARYO	Specify karyotype
26*	GENTEST	Genetic test
27*	SP_GENTEST	Specify genetic test
28	PM	Postmortem examination
29	SURGERY	First surgery for malformation performed or planned
30	SYNDROME	Syndrome
31	SP_SYNDROME	Specify syndrome
32	MALFO1	Malformation
33	SP_MALFO1	Specify malformation
34	MALFO2	As MALFO1
35	SP_MALFO2	Specify malformation
36	MALFO3	As MALFO1
37	SP_MALFO3	Specify malformation
38	MALFO4	As MALFO1
39	SP_MALFO4	Specify malformation
40	MALFO5	As MALFO1
41	SP_MALFO5	Specify malformation
42	MALFO6	As MALFO1
43	SP_MALFO6	Specify malformation
44	MALFO7	As MALFO1
45	SP_MALFO7	Specify malformation
46	MALFO8	As MALFO1
47	SP_MALFO8	Specify malformation
57	OMIM	OMIM code/type of Mendelian inheritance
Exposure and family history
58	ASSCONCEPT	Assisted conception (where available)
59†	OCCUPMO	Mother’s occupation at time of conception
Sociodemographic
91	MATEDU	Maternal education
92*	SOCM	Socioeconomic status of mother
93 *	SOCF	Socioeconomic status of father
94	MIGRANT	Migrant status
Derived variables
	Byear	Year of birth
	birth_type	Live birth, stillbirth, spontaneous abortion, TOPFA, not known definitions of stillbirths and spontaneous abortions vary between regions. This variable recodes birth type according to EUROCAT’s specifications: cases with gestational age ≥20 weeks are recoded as ‘stillbirths’ (irrespective of the local definition of stillbirth/spontaneous abortion).
	casestatus	Only cases with casestatus=1 or 2
	al1-al114	EUROCAT subgroups: (0=No, 1=Yes). Based on EUROCAT coding in Guide 1.4
	mult_malf	Algorithm for case classification into isolated and multiple anomalies

*See work of the Standardisation Committee (viii).
†EUROCAT Guide 1.4 use ISCO-08 classifications.
EDMP, EUROCAT Data Management Programme; TOOPFA, termination of pregnancy for a fetal anomaly.