Table 1

Pertussis vaccine uptake by social characteristics among pregnant women in England, 2012–2015

Total
(column %)
Received pertussis vaccine unadjusted coverage (row %)Minimally adjusted for year ‘minimally adjusted’ OR (95% CI)Model 1 additionally adjusted for IMD, region and ethnicity OR (95% CI)Model 2 additionally adjusted for maternal age OR (95% CI)Model 3 additionally adjusted for number of children ‘fully adjusted’ OR (95% CI)
Year
 20126717 (10.7)3809 (56.7)1111
 201324 657 (39.4)16 749 (67.9)1.62 (1.53 to 1.71)1.66 (1.57 to 1.75)1.66 (1.57 to 1.75)1.69 (1.60 to 1.79)
 201420 148 (32.2)13 638 (67.7)1.60 (1.51 to 1.69)1.63 (1.54 to 1.73)1.63 (1.54 to 1.73)1.66 (1.57 to 1.76)
 201511 015 (17.6)7903 (71.7)1.94 (1.82 to 2.07)2.00 (1.87 to 2.13)2.00 (1.87 to 2.13)2.03 (1.90 to 2.17)
Index of multiple deprivation (IMD) quintile
 Least deprived13 285 (21.2)10 090 (76.0)1111
 211 335 (18.1)8064 (71.1)0.78 (0.74 to 0.83)0.79 (0.74 to 0.83)0.80 (0.75 to 0.85)0.81 (0.76 to 0.86)
 312 933 (20.7)8807 (68.1)0.68 (0.64 to 0.71)0.68 (0.64 to 0.72)0.70 (0.66 to 0.74)0.73 (0.69 to 0.77)
 412 973 (20.7)8205 (63.2)0.54 (0.52 to 0.57)0.56 (0.53 to 0.59)0.59 (0.56 to 0.62)0.64 (0.60 to 0.67)
 Most deprived12 011 (19.2)6933 (57.7)0.43 (0.41 to 0.46)0.45 (0.42 to 0.47)0.48 (0.45 to 0.51)0.54 (0.51 to 0.57)
Region
 London11 894 (19.0)7239 (60.9)1111
 North East1185 (1.9)687 (58.0)0.91 (0.81 to 1.03)0.96 (0.85 to 1.09)1.00 (0.88 to 1.13)1.04 (0.92 to 1.19)
 North West8835 (14.1)5873 (66.5)1.29 (1.22 to 1.36)1.28 (1.20 to 1.35)1.30 (1.22 to 1.38)1.36 (1.27 to 1.44)
 Yorkshire and The Humber1000 (1.6)699 (69.9)1.51 (1.31 to 1.74)1.46 (1.27 to 1.69)1.51 (1.30 to 1.74)1.54 (1.33 to 1.79)
 East Midlands326 (0.5)243 (74.5)2.18 (1.69 to 2.81)2.24 (1.73 to 2.90)2.30 (1.78 to 2.98)2.38 (1.84 to 3.09)
 West Midlands7050 (11.3)5046 (71.6)1.64 (1.54 to 1.75)1.58 (1.48 to 1.69)1.62 (1.52 to 1.73)1.72 (1.61 to 1.84)
 East of England5568 (8.9)4058 (72.9)1.75 (1.63 to 1.88)1.50 (1.40 to 1.61)1.52 (1.41 to 1.63)1.57 (1.46 to 1.69)
 South West7002 (11.2)4800 (68.6)1.43 (1.34 to 1.52)1.32 (1.24 to 1.41)1.35 (1.26 to 1.44)1.43 (1.33 to 1.52)
 South Central10 381 (16.6)7185 (69.2)1.45 (1.37 to 1.53)1.19 (1.12 to 1.26)1.21 (1.15 to 1.29)1.28 (1.21 to 1.36)
 South East Coast9296 (14.9)6269 (67.4)1.33 (1.26 to 1.41)1.10 (1.04 to 1.17)1.12 (1.06 to 1.19)1.19 (1.12 to 1.26)
Ethnicity
 White52 598 (84.1)36 272 (69.0)1111
 South Asian4692 (7.5)2951 (62.9)0.76 (0.71 to 0.81)0.83 (0.78 to 0.88)0.79 (0.74 to 0.85)0.83 (0.78 to 0.88)
 Black2583 (4.1)1294 (50.1)0.45 (0.41 to 0.48)0.58 (0.54 to 0.64)0.56 (0.52 to 0.61)0.61 (0.56 to 0.67)
 Mixed922 (1.5)549 (59.5)0.65 (0.57 to 0.74)0.72 (0.63 to 0.82)0.71 (0.62 to 0.82)0.72 (0.63 to 0.83)
 Other1742 (2.8)1033 (59.3)0.65 (0.59 to 0.72)0.73 (0.66 to 0.80)0.70 (0.63 to 0.77)0.68 (0.62 to 0.75)
Maternal age, years
 <202079 (3.3)1153 (55.5)0.79 (0.72 to 0.87)0.80 (0.73 to 0.89)0.81 (0.73 to 0.89)
 20–248848 (14.1)5416 (61.2)111
 25–2916 696 (26.7)11 166 (66.9)1.27 (1.21 to 1.34)1.24 (1.18 to 1.31)1.29 (1.22 to 1.36)
 30–3520 294 (32.5)14 376 (70.8)1.54 (1.46 to 1.62)1.43 (1.35 to 1.51)1.55 (1.47 to 1.64)
 ≥3514 620 (23.4)9988 (68.3)1.36 (1.29 to 1.44)1.25 (1.18 to 1.32)1.42 (1.34 to 1.51)
Number of children
 026 622 (42.6)19 814 (74.4)11
 122 132 (35.4)14 673 (66.3)0.67 (0.65 to 0.70)0.65 (0.63 to 0.68)
 28645 (13.8)5009 (57.9)0.47 (0.45 to 0.49)0.47 (0.45 to 0.50)
 ≥35138 (8.2)2603 (50.7)0.35 (0.33 to 0.37)0.37 (0.35 to 0.40)
Body mass index (BMI)
 <18.5 underweight2063 (3.3)1265 (61.3)0.71 (0.64 to 0.77)
 18.5–24.929 045 (46.4)20 095 (69.2)1
 25.0–29.9 overweight14 211 (22.7)9852 (69.3)1.01 (0.96 to 1.05)
 ≥30 obese10 552 (16.9)6833 (64.8)0.82 (0.78 to 0.86)
 Missing6666 (10.7)4054 (60.8)
  • N=62 537 from 402 practices. Overall vaccine uptake 42 099 (67.3%).

  • All models include women who registered before the end of the first trimester and delivered a live or stillborn child on or after 26 weeks of pregnancy and exclude those with missing ethnicity; minimally adjusted model of BMI additionally excludes 6666 women with missing BMI.