Table 1

Patient characteristics

Hospital 1, Máxima MC
(n=389)
Hospital 2, Amphia Hospital
(n=361)
Total
(n=750)
P value
Demographics
 Sex, male, n (%)174 (48.6)189 (48.6)363 (48.6)0.996
 Age (years), mean (SD)67.4 (16.8)69.0 (14.7)68.2 (15.8)0.553
Comorbidities
 None, n (%)12 (3.1)32 (8.9)44 (5.9)0.001
 CCI, mean (SD)2.75 (2.21)2.81 (2.20)2.30 (2.12)0.778
 MI, n (%)44 (11.3)44 (12.2)88 (11.7)0.709
 Heart failure, n (%)40 (10.3)66 (18.3)106 (14.1)0.002
 Chronic pulmonary disease, n (%)149 (38.3)130 (36)279 (37.2)0.516
 CVA, n (%)49 (12.6)46 (12.7)95 (12.7)0.952
 PAD, n (%)26 (6.7)27 (7.5)53 (7.1)0.671
 DM, n (%)63 (16.2)62 (17.2)125 (16.7)0.719
 Dementia, n (%)24 (6.2)9 (2.5)33 (4.4)0.014
 Renal failure, n (%)34 (8.7)22 (6.1)56 (7.5)0.168
 Neoplasm, n (%)108 (27.8)83 (23.0)191 (25.5)0.134
Biomarkers
 CRP (mg/L), median (Q1–Q3)51 (16–151)76 (27–168.3)63 (21–163)0.014
 Leucocytes (×10ˆ9/L), median (Q1–Q3)11.8 (7.3–15.5)12.2 (7.8–15.7)12.1 (7.4–15.6)0.481
 Intravenous antibiotic treatment, n (%)229 (66.8)215 (72.6)444 (69.5)0.108
  • Values are expressed in n (number) and percentages, which denote the proportion within a group of patients. Data are expressed in mean (SD) or median (Q1–Q3, first quartile to third quartile). The χ2 test was used for categorical variables, the Mann-Whitney U test for continuous variables. Patients who did not receive intravenous antibiotics received oral antibiotics or were suspected of having a viral infection.

  • CCI, Charlson Comorbidity Index; MI, myocardial infarction; CVA, cerebrovascular accident; PAD, peripheral artery disease; DM, diabetes mellitus; CRP, C-reactive protein.;