Table 2

RR and RD results for comparisons of treatment intensity pairs

OutcomePlacebo – moderate IntensityModerate – high IntensityPlacebo – high Intensity
RR (95% CI)RD (95% CI)NNHRR (95% CI)RD (95% CI)NNHRR (95% CI)RD (95% CI)NNH
Any probs1.010 (0.988 to 1.033)0.000 (−0.001 to 0.001)1.039 (1.004 to 1.075)0.004 (−0.000 to 0.008)1.049 (1.010 to 1.089)0.004 (−0.001 to 0.008)
Myalgia1.090 (0.9997 to 1.188)0.001 (−0.000 to 0.001)1.041 (1.001 to 1.083)0.006 (0.001 to 0.010)1731.134 (1.046 to 1.230)0.007 (0.002 to 0.011)182
Attrition1.127 (0.931 to 1.364)0.001 (−000 to 0.001)1.372 (1.091 to 1.726)0.005 (0.002 to 0.007)2181.155 (1.147 to 2.084)0.005 (0.002 to 0.008)187
Rhabdomyolysis1.225 (0.624 to 2.405)−0.000 (−0.001 to 0.001)1.326 (0.487 to 3.614)0.002 (0.001 to 0.003)1.624 (0.579 to 4.553)0.002 (0.000 to 0.003)
CK >10 × ULN1.143 (0.686 to 1.905)−0.000 (−0.001 to 0.001)4.594 (2.320 to 9.098)0.002 (0.001 to 0.003)5275.252 (2.293 to 12.028)0.002 (0.000 to 0.003)589
  • NNH, number needed to harm; RD, risk difference; RR, relative risk.