Table 2

Crude and adjusted HRs (95% CI) in cohorts 1 and 2

CharacteristicsHR
Crude*P valueAdjusted*†P value
Cohort 1
HRs for rheumatoid arthritis in migraine with aura
Migraine1.32 (0.97 to 1.78)0.0781.23 (0.91 to 1.67)0.183
Control I1.001.00
HRs for rheumatoid arthritis in migraine without aura
Migraine1.52 (1.38 to 1.67)<0.001‡1.48 (1.34 to 1.63)<0.001‡
Control I1.001.00
Cohort 2
HR for migraine with aura
RA1.40 (0.98 to 2.01)0.0651.36 (0.95 to 1.96)0.094
Control II1.001.00
HR for migraine without aura
RA1.38 (1.26 to 1.53)<0.001‡1.35 (1.23 to 1.49)<0.001‡
Control II1.001.00
  • *Stratified model for age, sex, income and region of residence.

  • †Adjusted model for autoimmune disease, Charlson Comorbidity Index (except rheumatoid diseases), obesity (body mass index), smoking and alcohol intake histories.

  • ‡Cox-proportional hazard regression model, significance at p<0.05.

  • RA, rheumatoid arthritis.