Variables | Univariate regression | Multivariate regression model 1 | Multivariate regression model 2 | |||
OR (95% CI) | P value | AOR (95% CI) | P value | AOR (95% CI) | P value | |
Age, per 10 years, median (IQR) | 1.34 (1.16 to 1.56) | <0.001 | 1.26 (1.04 to 1.53) | 0.017 | 1.27 (1.57 to 4.13) | 0.016 |
Male | 1.49 (0.96 to 2.33) | 0.08 | NI | NI | ||
Medical history | NI | NI | ||||
Hypertension | 1.68 (0.73 to 3.64) | 0.199 | NI | NI | ||
Diabetes | 3.09 (1.19 to 7.88) | 0.017 | NI | NI | ||
Laboratory tests (median; IQR) | ||||||
White cells (×109/L) | 1.09 (1.06 to 1.13) | <0.001 | 1.08 (1.03 to 1.13) | <0.001 | 1.09 (1.04 to 1.54) | <0.001 |
Haemoglobin (g/L) | 1.02 (1.0 to 1.03) | 0.007 | NI | NI | ||
Platelets (×109/L) | 1.0 (1.0 to 1.0) | 0.577 | NI | NI | ||
Albumin (g/L) | 0.87 (0.83 to 0.9) | <0.001 | 0.89 (0.84 to 0.93) | <0.001 | 0.88 (0.84 to 0.93) | <0.001 |
pChe (per 100 U/L) | 0.89 (0.85 to 0.93) | <0.001 | 0.91 (0.86 to 0.95) | <0.001 | 0.91 (0.86 to 0.95) | <0.001 |
BUN (mmol/L) | 1.35 (1.21 to 1.52) | <0.001 | NI | NI | ||
sCr (per 0.1 mg/dL) | 1.26 (1.16 to 1.38) | <0.001 | 1.1 (1.0 to 1.23) | 0.076 | NI | |
Serum amylase (per 10 U/L) | 1.02 (1.02 to 1.03) | <0.001 | NI | NI | ||
Blood gas analysis (median; IQR) | ||||||
pH (per 0.1) | 0.42 (0.33 to 0.52) | <0.001 | 0.59 (0.45 to 0.74) | <0.001 | 0.55 (0.43 to 0.7) | <0.001 |
PCO2 (mm Hg) | 1.35 (1.15 to 1.64) | <0.001 | NI | NI | ||
PO2 (mm Hg) | 1.01 (0.97 to 1.05) | 0.516 | NI | NI | ||
Base excess (mmol/L) | 0.87 (0.83 to 0.9) | <0.001 | NI | NI | ||
Lactic acid (mmol/L) | 1.21 (1.09 to 1.34) | <0.001 | 1.18 (1.03 to 1.37) | 0.021 | 1.18 (1.02 to 1.37) | 0.022 |
AIC | NA | 322.62 | 324.36 |
Variables with p value less than 0.2 in univariate logistic regression were subjected to multivariate stepwise backward logistic regression. Model 1 was fitted with variables selected directly by stepwise regression. Model 2 was fitted with significant variables (p<0.05) in model 1.
AIC, Akaike’s information criterion; AOPP, acute organophosphorus poisoning; AOR, adjusted OR; BUN, blood urea nitrogen; NA, not available; NI, not included; pChe, plasma cholinesterase; PCO2, partial pressure of carbon dioxide; PO2, partial pressure of oxygen; sCr, serum creatinine.