Table 2

Comorbidities, outpatient medication, quality of care and exercise metrics of KPGA patients with COVID-19, by race/ethnicity

All
(N=5721)
Black
(n=3339)
White
(n=1689)
Hispanic
(n=487)
Asian
(n=206)
P value
Comorbidities, N (%)
HTN1816 (31.7)1160 (34.7)* **507 (30)†87 (17.9)†††62 (30.1)<0.0001
Diabetes898 (15.7)570 (17.1)* **229 (13.6)62 (12.7)37 (18)0.0022
Obesity (BMI >30)439 (7.7)300 (9)* ***102 (6)††32 (6.6)†††5 (2.4)<0.0001
Hyperlipidaemia1262 (22.1)667 (20)* ***453 (26.8)82 (16.8)†††60 (29.1)<0.0001
CAD285 (5)135 (4)*125 (7.4)†13 (2.7)†††12 (5.8)<0.0001
CHF320 (5.6)187 (5.6)* **121 (7.2)† ††6 (1.2)6 (2.9)<0.0001
Asthma574 (10)377 (11.3)* ** ***148 (8.8)35 (7.2)14 (6.8)0.0013
COPD153 (2.7)64 (1.9)*78 (4.6)†5 (1)6 (2.9)<0.0001
Arrhythmia172 (3)79 (2.4)* **85 (5)†3 (0.6)†††5 (2.4)<0.0001
ESRD‡4 (0.1)3 (0.1)1 (0.1)0 (0)0 (0)0.8726
HIV65 (1.1)54 (1.6)* **9 (0.5)1 (0.2)1 (0.5)0.0007
Depression633 (11.1)318 (9.5)*262 (15.5)† ††39 (8)14 (6.8)<0.0001
CKD§100 (1.8)62 (1.9)**31 (1.8)3 (0.6)4 (1.9)0.2632
Cancer93 (1.6)55 (1.7)33 (2)†3 (0.6)2 (1)0.1867
2+ comorbidities¶1823 (31.9)1095 (32.8)***570 (33.7)†90 (18.5)†††68 (33)<0.0001
3+ comorbidities¶966 (16.9)560 (16.8)* ***333 (19.7)†41 (8.4)†††32 (15.5)<0.0001
Charlson Comorbidity Index, mean (SD)‡‡1.9 (1.4)* **1.9 (1.5)2.1 (1.7)†1.5 (1.1)1.67 (1.2)0.0014
Outpatient medication, N (%)
Antirheumatic17 (0.3)8 (0.2)7 (0.4)2 (0.4)0 (0)0.5696
Antihypertensive1059 (18.5)632 (18.9)**329 (19.5)†62 (12.7)36 (17.5)0.0062
Antiasthmatic890 (15.6)533 (16)274 (16.2)57 (11.7)26 (12.6)0.3283
Antihyperlipidaemic1034 (18.1)543 (16.3)* ***371 (22)†65 (13.4)†††55 (26.7)<0.0001
Corticosteroids1244 (21.7)726 (21.7)*388 (23)†89 (18.3)41 (19.9)0.1478
Cough/cold medication788 (13.8)459 (13.8)249 (14.7)56 (11.5)24 (11.7)0.2367
Antimalarial31 (0.5)22 (0.7)*4 (0.2)4 (0.8)1 (0.5)0.2139
Quality of care metrics§§
Blood pressure >140/90¶¶501 (27.6)349 (30.1)**118 (23.3)†21 (24.1)†††13 (21)<0.0001
Diabetes uncontrolled (A1C>8)¶¶286 (31.8)195 (34.2)65 (28.4)18 (29)8 (21.6)0.1976
Average exercise minutes, mean (SD)‡‡‡79.9 (114)75.3 (113.4)*91 (128.1)76.7 (115.6)87.5 (99.7)0.0034
EVS category, N (%)§§§
Inactive1648 (28.8)998 (29.9)460 (27.2)136 (27.9)54 (26.2)0.0044
Insufficient1336 (23.4)814 (24.4%)*359 (21.3)107 (22)56 (27.2)
Sufficient785 (13.7)432 (12.9)*265 (15.7)†57 (11.7)31 (15.1)
No information1952 (34.1)1095 (32.8)* **605 (35.8)187 (38.4)65 (31.6)
  • Significance levels: *Black vs white; **Black vs Hispanic; ***Black vs Asian; †White vs Hispanic; ††White vs Asian; †††Hispanic vs Asian, significant difference at p<0.05.

  • ‡ESRD classified based on diagnosis reported by the 10th revision of the International Statistical Classification of Diseases and Related Health Problems code (ICD-10) in patient’s medical history.

  • §CKD classified based on diagnosis reported by the ICD-10 code in patient’s medical history.

  • ¶Comorbidities here are medical diagnoses included in medical history as ICD-10 codes. These include, but are not limited to, those presented in the table.

  • ‡‡Charlson Comorbidity Index predicts the 10-year mortality of a patient based on age and comorbidities. Scores are summed to provide a total predictive score. The lowest score of 0 corresponds to a 98% estimated 10-year survival rate (Charlson et al 1987).

  • §§Assessed at the most recent clinical encounter within the last 12 months.

  • ¶¶Blood pressure control was evaluated only among patients with hypertension (n=1816) and glucose control among patients with diabetes (n=898).

  • ‡‡‡Average exercise was collected from self-reported data.

  • §§§EVS is based on patient-reported weekly exercise minutes. We used three categories: inactive for patients who reported less than 10 min/week; insufficiently active for patients who reported 11–149 min/week; and sufficiently active for patients who reported 150 or more min/week.

  • BMI, body mass index; CAD, coronary artery disease; CHF, congestive heart failure; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; ESRD, end-stage renal disease; EVS, exercise as a vital sign; HbA1c, glycated haemoglobin; HTN, hypertension; KPGA, Kaiser Permanente Georgia.