CVD | CHD | Mortality | ||||
HR*† | 95% CI | HR* | 95% CI | HR* | 95% CI | |
No of siblings (ref. non-sibling) | ||||||
One sibling | 0.98 | 0.98 to 0.99 | 0.99 | 0.97 to 1.02 | 0.94 | 0.93 to 0.95 |
Two siblings | 0.99 | 0.98 to 1 | 1.03 | 1 to 1.06 | 0.92 | 0.91 to 0.94 |
Three siblings | 1 | 0.99 to 1.01 | 1.07 | 1.04 to 1.11 | 0.93 | 0.91 to 0.95 |
Four or more siblings | 1.01 | 1 to 1.03 | 1.17 | 1.13 to 1.21 | 0.95 | 0.93 to 0.96 |
Birth order (ref. first birth) | ||||||
Second | 1.01 | 1 to 1.02 | 1.07 | 1.05 to 1.09 | 0.96 | 0.95 to 0.98 |
Third | 1.02 | 1.01 to 1.03 | 1.14 | 1.11 to 1.18 | 0.98 | 0.96 to 1 |
Fourth | 1.04 | 1.02 to 1.05 | 1.14 | 1.09 to 1.2 | 1 | 0.98 to 1.03 |
Fifth+ | 1.05 | 1.03 to 1.07 | 1.22 | 1.15 to 1.29 | 1.03 | 0.99 to 1.07 |
*Full adjusted model: Adjusted for age at start, individual characteristics of family income, marital status, educational attainment, immigrant status, socioeconomic status, region of residence, comorbidities, number of siblings, and birth order.
†Multivariable competing risk survival analysis.
CHD, coronary heart disease; CVD, cardiovascular disease.