Schedule of events
| Preclinical | Preoperative | CABG | Postoperative | Follow-up | ||||
| Timing: | T0 | T1 | T2 | T3 | T4 | T5 | T6 | |
| Baseline | Stop ECC | Stop ECC+6 hours | Incision+24 hours | CABG +3–7days | 6 weeks | 6 months | ||
| Inclusion/exclusion criteria | X | |||||||
| Informed consent | X | |||||||
| TSPO binding affinity | X | |||||||
| PET/CT cerebrum | X | X | ||||||
| MRI cerebrum | X | X | ||||||
| Blood sampling | X | X | X | X | X | X | ||
| Neuropsychological assessment | X | X | X | X | ||||
| Delirium assessment | 3 times daily during hospital stay | |||||||
CABG, coronary artery bypass grafting; ECC, extracorporeal circulation; MRI, magnetic resonance imaging; PET/CT, positron emission tomography/computated tomography; TSPO, translocator protein.