Table 3

Treatment and outcomes of patients

VariableAll patients (n=522 167)*ICU admission (n=172 473)Non-ICU admission (n=293 384)Not reported (n=56 310)P valueSurvivor and non-COVID-19 death (n=297 043)Non-survivor (n=160 495)Still in the hospital (n=53 503)P value
Treatment with drugs, number (%)<0.001<0.001
 Oseltamivir82 659 (15.8)30 341 (17.6)47 317 (16.1)5001 (8.9)50 091 (16.9)27 192 (16.9)4242 (7.9)
 Zanamivir492 (0.1)152 (0.1)303 (0.1)37 (0.1)298 (0.1)128 (0.1)56 (0.1)
 Other5008 (1.0)1480 (0.9)3243 (1.1)285 (0.5)3029 (1.0)1118 (0.7)701 (1.3)
Mechanical ventilation, number (%)<0.001<0.001
 Invasive90 189 (17.3)75 915 (44.0)12 019 (4.1)2255 (4.0)17 263 (5.8)66 652 (41.5)5238 (9.8)
 Non-invasive234 554 (44.9)65 281 (37.9)157 913 (53.8)11 360 (20.2)148 930 (50.1)54 652 (34.1)25 925 (48.5)
ICU admission, number (%)172 473 (33.0)172 473 (100.0)65 102 (21.9)89 264 (55.6)15 614 (29.2)<0.001
 Remained hospitalised after ICU discharge, number (%)32 770 (19.0)32 770 (19.0)27 775 (42.7)3243 (3.6)1303 (8.4)<0.001
 Median length (IQR), days5 (2–10)5 (2–10)5 (2–9)7 (2–16)72 (21–139)<0.001
Median times (IQR), days
 Illness onset to treatment with drugs5 (3–8)5 (3–8)6 (3–9)6 (3–8)<0.0016 (3–9)5 (2–8)6 (3–9)<0.001
 Illness onset to hospitalisation6 (3–9)6 (3–9)6 (3–10)6 (2–9)<0.0017 (3–10)5 (2–8)6 (3–10)<0.001
 Illness onset to ICU admission7 (3–10)7 (3–10)7 (4–10)6 (3–10)7 (3–10)<0.001
 Hospital admission to ICU admission0 (0–1)0 (0–1)0 (0–1)0 (0–1)0 (0–0)<0.001
 Illness onset to death15 (9–24)17 (10–25)13 (7–21)12 (7–20)<0.00115 (9–24)
 Illness onset to hospital discharge15 (11–20)18 (13–27)14 (10–18)16 (11–21)<0.00115 (11–20)
 Hospital admission to death9 (4–16)10 (5–18)7 (2–14)5 (1–13)<0.0019 (4–16)
 Hospital admission to ICU discharge9 (4–17)9 (4–17)7 (4–14)10 (5–10)6 (2–14)<0.001
 ICU admission to death9 (4–16)9 (4–16)9 (4–16)
Median length hospital stay (IQR), days8 (4–17)12 (6–22)7 (4–13)8 (3–18)<0.0017 (4–12)9 (4–16)79 (23–157)<0.001
Median length ICU stay (IQR), days8 (3–15)8 (3–15)6 (3–12)9 (4–16)4 (2–11)<0.001
Clinical outcomes as of 14 December 2020, number (%)<0.001
 Cured and discharged from hospital296 002 (56.7)64 578 (37.4)202 042 (68.9)29 382 (52.2)296 002 (99.7)
 Death due to other causes1041 (0.2)524 (0.3)443 (0.2)74 (0.1)1041 (0.4)
 Death associated with COVID-19160 495 (30.7)89 264 (51.8)53 282 (18.2)17 949 (31.9)160 495 (100.0)
 Still in the hospital53 503 (10.3)15 614 (9.1)30 963 (10.6)6926 (12.3)53 503 (100.0)
  • *Includes 11 126 patients with unknown clinical outcome.

  • †Non-survivors are classified as those whose death was associated with COVID-19, according to the SIVEP-Gripe database. Those who had COVID-19 but died due to an unrelated cause are classified under ‘Survivor & non-COVID-19 death’. Survivor n=296 002, non-COVID-19 death=1041.

  • ICU, intensive care unit.