Table 1

Distribution of different population sets and HRs from Cox models and ORs from logistic models and corresponding 95% CIs for several outcomes

Age class (years)Population not includedIncluded but not contactedIncluded and contactedTotalOverall
mortality		COVID-19
morbidity		COVID-19
hospitalisation
N (%)N (%)N (%)NHR (95% CI)OR (95% CI)HR (95% CI)OR (95% CI)HR (95% CI)OR (95% CI)
 70–74167 516
(33.8)		16 049
(20.29)		9370
(19.27)		192 9351#1#1#1#1#1#
 75–79125 115
(25.24)		17 347
(21.93)		10 501
(21,6)		152 9631.67
(1.54 to 1.82)		1.72
(1.57 to 1.89)		1.28
(1.19 to 1.39)		1.28
(1.19 to 1.39)		1.27
(1.17 to 1.38)		1.27
(1.17 to 1.38)
 80–84108 993
(21.99)		20 564
(25.99)		12 778
(26.28)		142 3352.36
(2.18 to 2.56)		2.56
(2.34 to 2.80)		1.55
(1.43 to 1.67)		1.54
(1.43 to 1.66)		1.40
(1.29 to 1.51)		1.39
(1.28 to 1.51)
 85–8960 515
(12.21)		15 646
(19.78)		9863
(20.28)		86 0244.20
(3.87 to 4.55)		5.21
(4.76 to 5.69)		2.13
(1.97 to 2.31)		2.12
(1.95 to 2.29)		1.84
(1.69 to 2.01)		1.82
(1.67 to 1.99)
 90+33 530
(6.76)		9504
(12.01)		6113
(12.57)		49 1477.53
(6.95 to 8.15)		10.98
(10.05 to 12.00)		2.37
(2.16 to 2.60)		2.32
(2.12 to 2.55)		1.66
(1.49 to 1.85)		1.61
(1.45 to 1.80)
Gender
 Males199 309
(40.21)		38 732
(48.96)		23 808
(48.96)		261 8491#1#1#1#1#1#
 Females296 360
(59.79)		40 378
(51.04)		24 817
(51.04)		361 5550.40
(0.38 to 0.42)		0.32
(0.31 to 0.34)		0.53
(0.50 to 0.56)		0.54
(0.51 to 0.56)		0.43
(0.41 to 0.46)		0.44
(0.41 to 0.46)
Polytherapy
 No polytherapy/
 
 no hypertherapy		238 072
(48.03)		9579
(12.11)		4758
(9.79)		252 4091#1#1#1#1#1#
 Polytherapy189 447
(38.22)		31 729
(40.11)		19 038
(39.15)		240 2142.78
(2.61 to 2.96)		2.76
(2.58 to 2.94)		1.67
(1.57 to 1.78)		1.65
(1.55 to 1.76)		1.86
(1.73 to 1.99)		1.83
(1.71 to 1.97)
 Hypertherapy68 150
(13.75)		37 802
(47.78)		24 829
(51.06)		130 7818.38
(7.84 to 8.96)		10.27
(9.57 to 11.02)		3.14
(2.92 to 3.38)		3.04
(2.82 to 3.28)		3.64
(3.35 to 3.95)		3.51
(3.24 to 3.81)
IBD and cirrhosis
 No492 858
(99.43)		76 125
(96.23)		46 724
(96.09)		615 7071#1#1#1#1#1#
 Yes2811
(0.57)		2985
(3.77)		1901
(3.91)		769732.69
(10.54 to 101.46)		66.57
(19.92 to 222.48)		1.13
(0.91 to 1.40)		1.10
(0.88 to 1.36)		1.19
(0.94 to 1.51)		1.16
(0.91 to 1.47)
COPD
 No472 949
(95.42)		63 154
(79.83)		38 018
(78.19)		574 1211#1#1#1#1#1#
 Yes22 720
(4.58)		15 956
(20.17)		10 607
(21.81)		49 28334.64
(24.81 to 48.36)		53.97
(38.26 to 76.12)		1.67
(1.52 to 1.85)		1.62
(1.47 to 1.78)		1.56
(1.41 to 1.73)		1.50
(1.36 to 1.67)
Renal failure
 No490 711
(99)		69 669
(88.07)		42 293
(86.98)		602 6731#1#1#1#1#1#
 Yes4958
(1)		9441
(11.93)		6332
(13.02)		20 7319.31
(6.40 to 13.54)		50.29
(37.54 to 67.37)		1.73
(1.49 to 2.01)		1.66
(1.43 to 1.93)		1.72
(1.47 to 2.03)		1.65
(1.40 to 1.94)
Diabetes
 No426 120
(85.97)		60 642
(76.66)		36 973
(76.04)		523 7351#1#1#1#1#1#
 Yes69 549
(14.03)		18 468
(23.34)		11 652
(23.96)		99 66937.64
(28.24 to 50.16)		93.23
(76.82 to 113.15)		1.69
(1.56 to 1.82)		1.64
(1.52 to 1.77)		1.70
(1.57 to 1.84)		1.65
(1.52 to 1.79)
Cardiovascular
 No402 378
(81.18)		18 878
(23.86)		9958
(20.48)		431 2141#1#1#1#1#1#
 Yes93 291
(18.82)		60 232
(76.14)		38 667
(79.52)		192 19059.98
(49.76 to 72.31)		374.8
(275.5 to 509.9)		2.15
(2.02 to 2.29)		2.07
(1.95 to 2.21)		2.33
(2.17 to 2.49)		2.24
(2.09 to 2.40)
Neoplasms
 No405 885
(81.89)		57 383
(72.54)		34 658
(71.28)		497 9261#1#1#1#1#1#
 Yes89 784
(18.11)		21 727
(27.46)		13 967
(28.72)		125 478115.9
(87.4 to 153.6)		39.88
(20.56 to 77.34)		2.02
(1.86 to 2.19)		1.95
(1.80 to 2.12)		2.06
(1.89 to 2.25)		1.99
(1.82 to 2.17)
Autoimmune diseases
 No479 704
(96.78)		74 124
(93.7)		45 350
(93.26)		599 1781#1#1#1#1#1#
 Yes15 965
(3.22)		4986
(6.3)		3275
(6.74)		24 22632.16
(16.72 to 61.85)		36.5
(19.0 to 70.2)		1.89
(1.59 to 2.25)		1.86
(1.57 to 2.22)		1.90
(1.58 to 2.29)		1.87
(1.55 to 2.26)
Charlson index
 0475 526
(95.94)		60 557
(76.55)		37 173
(76.45)		573 2561#1#1#1#1#1#
 15722
(1.15)		6896
(8.72)		4121
(8.48)		16 7397.88
(7.24 to 8.58)		14.11
(12.50 to 15.94)		3.21
(2.89 to 3.56)		3.10
(2.79 to 3.45)		2.70
(2.39 to 3.04)		2.59
(2.29 to 2.92)
 21345
(0.27)		3246
(4.1)		2019
(4.15)		66108.35
(7.46 to 9.35)		20.12
(16.67 to 24.28)		3.82
(3.27 to 4.47)		3.61
(3.08 to 4.24)		3.95
(3.35 to 4.65)		3.72
(3.15 to 4.40)
 3489
(0.1)		1377
(1.74)		849
(1.75)		27157.98
(6.81 to 9.35)		25.87
(19.14 to 34.96)		3.76
(2.98 to 4.74)		3.48
(2.74 to 4.42)		3.25
(2.49 to 4.24)		2.96
(2.26 to 3.88)
 4111
(0.02)		383
(0.48)		232
(0.48)		72612.50
(9.33 to 16.75)		60.20
(30.39 to 119.23)		5.59
(3.82 to 8.17)		5.29
(3.57 to 7.84)		3.52
(2.14 to 5.79)		3.22
(1.94 to 5.36)
 5+12 476
(2.52)		6651
(8.41)		4231
(8.7)		23 35813.21
(12.22 to 14.30)		48.32
(41.80 to 55.86)		2.17
(1.91 to 2.46)		2.03
(1.79 to 2.31)		2.05
(1.79 to 2.36)		1.92
(1.67 to 2.20)
Influenza vaccination
 No255 513
(51.55)		34 658
(43.81)		16 989
(34.94)		307 1601#1#1#1#1#1#
 Yes240 156
(48.45)		44 452
(56.19)		31 636
(65.06)		316 2441.08
(1.03 to 1.13)		1.09
(1.03 to 1.15)		0.97
(0.92 to 1.03)		0.97
(0.92 to 1.02)		0.89
(0.84 to 0.95)		0.89
(0.84 to 0.94)
Pneumococcal vaccination
 No468 588
(94.54)		70 699
(89.37)		41 630
(85.61)		580 9171#1#1#1#1#1#
 Yes27 081
(5.46)		8411
(10.63)		6995
(14.39)		42 4870.79
(0.73 to 0.85)		0.71
(0.64 to 0.78)		0.98
(0.89 to 1.08)		0.99
(0.90 to 1.09)		0.95
(0.86 to 1.05)		0.96
(0.87 to 1.06)
Total495 669
(79.51)		79 110
(12.69)		48 625
(7.8%)		623 404    C-index 0.93   C-index 0.70    C-index 0.68

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