Table 1

Outcome measures

Primary outcomeSecondary outcomes
Total blood loss (mL)Blood transfusion rate (mL)
Drainage volume (mL)
Plasma D-dimer (mg/L)
Plasma PAI-1 (ng/mL)
Plasma TAT (ng/mL)
Plasma F1+2 (ng/mL)
Wound complications
Venous thromboembolism
Length of hospital stay (days)
  • F1+2, prothrombin fragment F1+2; PAI-1, plasminogen activator inhibitor-1; TAT, thrombin–antithrombin complexes.