Table 1

Summary of descriptions and discussion points for open-label placebo (OLP) and conventional placebo (CP)

Discussion pointOLPCP
What is this treatment?Placebo capsules containing no active ingredient.A new pharmacological agent, (drug codename).
What does previous research say?Placebo effects have been found to reduce insomnia symptoms, but deception is typically involved. Some recent studies in other countries have shown OLP effects outside of sleep.Some recent studies in other countries have shown that (drug codename) can reduce insomnia symptoms.
What are the mechanisms of action?Placebo effects trigger the brain to release neurotransmitters that can improve symptoms. These responses can be automatic.(Drug codename) triggers the brain to release neurotransmitters that can improve sleep.
How should I take the capsules?Work best if taken exactly as prescribed. A positive attitude helps, but is not essential.
How long will it take to work?Generally work quickly, but can take longer for some people.