Base-case and sensitivity analyses of stroke aftercare vs care-as-usual, incremental cost-effectiveness ratios and plane distributions
Sample size | Total costs (€) | Total effects | Cost-effectiveness | Distribution CE-plane (%, quadrant) | ||||||||||
Analysis | Effect measure/ sensitivity analysis | Stroke aftercare | Care-as-usual | Stroke aftercare | Care-as-usual | Stroke aftercare | Care-as-usual | ∆Total costs (€) | ∆Effects | ICUR/ ICER | NE | SE dominant | SW | NW inferior |
Base case | QALY | 84 | 306 | 17 682.1 | 16 510.3 | 0.59 | 0.54 | 1171.8 | 0.05 | 24 678.6 | 65 | 34 | 0 | 1 |
Sensitivity | TIA exclusion | 71 | 306 | 17 399.6 | 16 510.3 | 0.59 | 0.54 | 889.3 | 0.05 | 20 595.2 | 62 | 37 | 0 | 1 |
Costs correction T1 | 84 | 306 | 17 682.1 | 15 273.1 | 0.59 | 0.54 | 2408.9 | 0.05 | 50 733.9 | 80 | 19 | 0 | 0 | |
50% increase | 84 | 306 | 17 727.6 | 16 510.3 | 0.59 | 0.54 | 1217.3 | 0.05 | 25 638.1 | 66 | 33 | 0 | 1 | |
Dutch tariffs | 84 | 306 | 17 682.1 | 16 510.3 | 0.62 | 0.57 | 1171.8 | 0.05 | 27 103.7 | 67 | 33 | 0 | 0 | |
Base case | HADS total | 84 | 306 | 17 682.1 | 16 510.3 | 32.61 | 32.57 | 1171.8 | 0.04 | 27 709.6 | 30 | 22 | 12 | 36 |
Sensitivity | TIA exclusion | 71 | 306 | 17 399.6 | 16 510.3 | 32.37 | 32.57 | 889.3 | −0.20 | −4521.1 | 21 | 19 | 19 | 41 |
Correction T1 | 84 | 306 | 17 682.1 | 15 273.1 | 32.61 | 32.57 | 2408.9 | 0.04 | 56 965.0 | 40 | 14 | 7 | 40 | |
50% increase | 84 | 306 | 17 727.6 | 16 510.3 | 32.61 | 32.57 | 1217.3 | 0.04 | 28 786.9 | 30 | 22 | 13 | 35 | |
HADS anxiety | 84 | 306 | 17 682.1 | 16 510.3 | 16.42 | 16.37 | 1171.8 | 0.05 | 24 513.5 | 33 | 23 | 12 | 33 | |
HADS depression | 84 | 306 | 17 682.1 | 16 510.3 | 16.19 | 16.20 | 1171.8 | −0.01 | −25 2001.6 | 29 | 21 | 13 | 37 | |
Base case | USER-P | 84 | 306 | 17 682.1 | 16 510.3 | 85.46 | 80.55 | 1171.8 | 4.91 | 238.6 | 66 | 34 | 0 | 0 |
Sensitivity | TIA exclusion | 71 | 306 | 17 399.6 | 16 510.3 | 84.95 | 80.55 | 889.3 | 4.40 | 201.9 | 60 | 39 | 0 | 1 |
Correction T1 | 84 | 306 | 17 682.1 | 15 273.1 | 85.46 | 80.55 | 2409.9 | 4.91 | 490.6 | 81 | 19 | 0 | 0 | |
50% increase | 84 | 306 | 17 727.6 | 16 510.3 | 85.46 | 80.55 | 1217.3 | 4.91 | 247.9 | 67 | 33 | 0 | 0 |
CE-plane, cost-effectiveness plane; HADS, Hospital Anxiety and Depression Scale; ICER, incremental cost-effectiveness ratio; ICUR, incremental cost-utility ratio; NE, north-east; NW, north-west; QALY, quality adjusted life year; SE, south-east; SW, south-west; USER-P, Utrecht Scale for Evaluation of Rehabilitation-Participation.