Baseline characteristics of participants
Proportion (%), unless otherwise specified | Group 1 (n=15) | Group 2 (n=15) | Group 3 (n=16) | Total (n=46) |
Age in years, mean (SD) (range) | 52.4 (21.4) (18–81) | 52.4 (22.4) (19–81) | 40.8 (14.0) (20–63) | 48.3 (19.9) (18–81) |
Previous UTI | ||||
Yes | 12/15 (80%) | 12/13 (92.3%) | 11/13 (84.6%) | 35/41 (85.4%) |
No | 3/15 (20%) | 1/13 (7.7%) | 2/13 (15.4%) | 6/41 (14.6) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Previous UTI in the past year | ||||
Yes | 7/15 (46.7%) | 6/13 (46.2%) | 6/13 (46.2%) | 19/41 (46.3%) |
No | 5/15 (33.3%) | 6/13 (46.2%) | 5/13 (38.5%) | 16/41 (39.0%) |
N/A (have never had a previous UTI) | 3/15 (20%) | 1/13 (7.7%) | 2/13 (15.4%) | 6/41 (14.6%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
If had a UTI in the past year, number of months since last UTI—mean (SD), median (range) | 5.4 (4.5), 4 (0–12) n=7 | 5 (4.2), 5 (0–11) n=5 | 7 (3.6), 7 (3–12) n=5 | 5.8 (4.2), 5 (0–12) n=17 |
Can’t remember | 0/15 (0%) | 1/13 (7.7%) | 1/12 (8.3%) | 2/40 (5%) |
Not applicable | 8/15 (53.3%) | 7/13 (53.9%) | 6/12 (50%) | 21/40 (52.5%) |
Missing | 0/15 | 2/15 | 4/16 | 6/46 |
Number of UTIs in the past year | ||||
0 | 5/15 (33.3%) | 7/13 (53.9%) | 4/13 (30.8%) | 16/41 (39.0%) |
1 | 3/15 (20%) | 2/13 (15.4%) | 5/13 (38.5%) | 10/41 (24.4%) |
2 | 2/15 (13.3%) | 2/13 (15.4%) | 1/13 (7.7%) | 5/41 (12.2%) |
3 or more | 2/15 (13.3%) | 1/13 (7.7%) | 1/13 (7.7%) | 4/41 (9.8%) |
Not applicable (have never had a previous UTI) | 3/15 (20%) | 1/13 (7.7%) | 2/13 (15.4%) | 6/41 (14.6%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Were you expecting antibiotic treatment? | ||||
Yes | 13/15 (86.7%) | 10/13 (76.9%) | 8/13 (61.5%) | 31/41 (75.6%) |
No | 0/15 (0%) | 1/13 (7.7%) | 1/13 (7.7%) | 2/41 (4.9%) |
Unsure | 2/15 (13.3%) | 2/13 (15.4%) | 4/13 (30.8%) | 8/41 (19.5%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Were you expecting tests/investigations? | ||||
Yes | 12/15 (80%) | 10/13 (76.9%) | 8/13 (61.5%) | 30/41 (73.2%) |
No | 3/15 (20%) | 3/13 (23.1%) | 4/13 (30.8%) | 10/41 (24.4%) |
Unsure | 0/15 (0%) | 0/13 (0%) | 1/13 (7.7%) | 1/41 (2.4%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Were you expecting advice? | ||||
Yes | 12/15 (80%) | 11/12 (91.7%) | 13/13 (100%) | 36/40 (90%) |
No | 2/15 (13.3%) | 1/12 (8.3%) | 0/13 (0%) | 3/40 (7.5%) |
Unsure | 1/15 (6.7%) | 0/12 (0%) | 0/13 (0%) | 1/40 (2.5%) |
Missing | 0/15 | 3/15 | 3/16 | 6/46 |
Were you expecting something else? | ||||
Yes | 0/15 (0%) | 1/13 (7.7%)—information and prescription (1 participant) | 0/13 (0%) | 1/41 (2.4%) |
No | 15/15 (100%) | 10/13 (76.9%) | 11/13 (84.6%) | 36/41 (87.8%) |
Unsure | 0/15 (0%) | 2/13 (15.4%) | 2/13 (15.4%) | 4/41 (9.8%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Was your last UTI treated with antibiotics? | ||||
Yes | 8/15 (53.3%) | 9/13 (69.2%) | 10/13 (76.9%) | 27/41 (65.9%) |
No | 4/15 (26.7%) | 3/13 (23.1%) | 1/13 (7.7%) | 8/41 (19.5%) |
Not applicable | 3/15 (20%) | 1/13 (7.7%) | 2/13 (15.4%) | 6/41 (14.6%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Was your last UTI treated with something other than antibiotics? | ||||
Yes | 2/15 (13.3%)— cystitis sachets (2 participants) | 1/13 (7.7%)—cystitis sachets (1 participant) | 0/13 (0%) | 3/41 (7.3%) |
No | 10/15 (66.7%) | 11/13 (84.6%) | 11/13 (84.6%) | 32/41 (78.1%) |
Not applicable | 3/15 (20%) | 1/13 (7.7%) | 2/13 (15.4%) | 6/41 (14.6%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Did you receive no treatment for your last UTI? | ||||
Yes | 1/15 (6.7%) | 0/13 (0%) | 0/13 (0%) | 1/41 (2.4%) |
No | 11/15 (73.3%) | 12/13 (92.3%) | 11/13 (84.6%) | 34/41 (82.9%) |
Not applicable | 3/15 (20%) | 1/13 (7.7%) | 2/13 (15.4%) | 6/41 (14.6%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Unable to remember how last UTI was treated | ||||
Yes | 1/15 (6.7%) | 1/13 (7.7%) | 1/13 (7.7%) | 3/41 (7.3%) |
No | 11/15 (73.3%) | 11/13 (84.6%) | 10/13 (76.9%) | 32/41 (78.1%) |
Not applicable | 3/15 (20%) | 1/13 (7.7%) | 2/13 (15.4%) | 6/41 (14.6%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Treatments tried before consulting primary care | ||||
Cranberry products | ||||
Yes | 2/15 (13.3%) | 3/13 (23.1%) | 3/13 (23.1%) | 8/41 (19.5%) |
No | 13/15 (86.7%) | 10/13 (76.9%) | 10/13 (76.9%) | 33/41 (80.5%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Other fruit juice | ||||
Yes | 1/15 (93.3%) | 1/13 (7.7%) | 0/13 (0%) | 2/41 (4.9%) |
No | 14/15 (93.3%) | 12/13 (92.3%) | 13/13 (100%) | 39/41 (95.1%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Bicarbonate solution | ||||
Yes | 0/15 (0%) | 0/13 (0%) | 0/13 (0%) | 0/41 (0%) |
No | 15/15 (100%) | 13/13 (100%) | 13/13 (100%) | 41/41 (100%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Sodium/potassium citrate (cystitis sachets) | ||||
Yes | 3/15 (20%) | 7/13 (53.9%) | 1/13 (7.7%) | 11/41 (26.8%) |
No | 12/15 (80%) | 6/13 (46.2%) | 12/13 (92.3%) | 30/41 (73.2%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Uvacin/uva ursi (bearberry) | ||||
Yes | 0/15 (0%) | 0/13 (0%) | 0/13 (0%) | 0/41 (0%) |
No | 15/15 (100%) | 13/13 (100%) | 13/13 (100%) | 41/41 (100%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Pain relief (eg, paracetamol/ibuprofen) | ||||
Yes | 6/15 (40%) | 7/13 (53.9%) | 4/13 (30.8%) | 17/41 (41.5%) |
No | 9/15 (60%) | 6/13 (46.2%) | 9/13 (69.2%) | 24/41 (58.5%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Other treatment used? | ||||
Yes | 2/15 (13.3%)— water (2 participants) | 2/13 (15.4%)— tea tree in bath (1 participant); sachets (1 participant) | 2/13 (15.4%)— water (2 participants) | 6/41 (14.6%) |
No | 13/15 (86.7%) | 11/13 (84.6%) | 11/13 (84.6%) | 35/41 (85.4%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
None | ||||
Yes | 7/15 (46.7%) | 2/13 (15.4%) | 5/13 (38.5%) | 14/41 (34.2%) |
No | 8/15 (53.3%) | 11/13 (84.6%) | 8/13 (61.5%) | 27/41 (65.9%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Number of days symptomatic | ||||
0 | 1/15 (6.7%) | 2/13 (15.4%) | 1/13 (7.7%) | 4/41 (9.8%) |
1 | 3/15 (20%) | 1/13 (7.7%) | 2/13 (15.4%) | 6/41 (14.6%) |
2 | 4/15 (26.7%) | 3/13 (23.1%) | 5/13 (38.5%) | 12/41 (29.3%) |
3 | 2/15 (13.3%) | 2/13 (15.4%) | 4/13 (30.8%) | 8/41 (19.5%) |
>3 | 5/15 (33.3%) | 5/13 (38.5%) | 1/13 (7.7%) | 11/41 (26.8%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Belief that cranberry can help symptoms | ||||
Yes | 10/15 (66.7%) | 7/13 (53.9%) | 8/13 (61.5%) | 25/41 (61%) |
No | 1/15 (6.7%) | 0/13 (0%) | 0/13 (0%) | 1/41 (2.4%) |
Unsure | 4/15 (26.7%) | 6/13 (46.2%) | 5/13 (38.5%) | 15/41 (36.6%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Belief that symptoms can get better without antibiotics | ||||
Yes | 5/15 (33.3%) | 1/13 (7.7%) | 4/13 (30.8%) | 10/41 (24.4%) |
No | 4/15 (26.7%) | 4/13 (30.8%) | 2/13 (15.4%) | 10/41 (24.4%) |
Unsure | 6/15 (40%) | 8/13 (61.5%) | 7/13 (53.9%) | 21/41 (51.2%) |
Missing | 0/15 | 2/15 | 3/16 | 5/46 |
Group 1—immediate antibiotics alone (control); group 2—immediate antibiotics and immediate cranberry; group 3—immediate cranberry and delayed antibiotics.
N/A, not applicable; UTI, urinary tract infection.