Variable | Effect | Calretinin ELISA ≥0.6 ng/mL | Mesothelin CLEIA ≥1.5 nM | Mesothelin ELISA ≥2.0 nM | ||||||
n* | POR† | 95% CI | n* | POR† | 95% CI | n* | POR† | 95% CI | ||
Age (years) | – | – | 23 | 1.06 | 0.99 to 1.14 | 23 | 1.07 | 1.00 to 1.16 | ||
Cystatin C (mg/dL) (reference: ≤sv‡) | >sv‡ | 5 | 17.5 | 4.40 to 69.7 | 11 | 12.1 | 4.46 to 33.0 | 10 | 9.58 | 3.46 to 26.5 |
C reactive protein (mg/dL) (reference: ≤sv‡) | >sv‡ | – | – | 11 | 2.25 | 0.87 to 5.84 | 12 | 3.00 | 1.17 to 7.67 | |
Haemoglobin A1c (%) (reference: ≤sv‡) | >sv‡ | – | – | 11 | 0.76 | 0.28 to 2.03 | 10 | 0.60 | 0.22 to 1.64 | |
Current hypertension (reference: no) | Yes | 8 | 3.00 | 0.36 to 25.3 | 21 | 4.40 | 0.95 to 20.4 | 21 | 4.63 | 1.01 to 21.2 |
Current bronchitis (reference: no) | Yes | – | – | 3 | 6.13 | 1.10 to 34.1 | 3 | 7.38 | 1.35 to 40.3 |
Statistically significant results are marked in bold.
*Men with positive marker result and with blood parameters above/below standard values (sv) or disease.
†Prevalence ORs (PORs) with 95% CI.
‡The sv of blood parameters are given in online supplemental table S1.
CLEIA, chemiluminescent enzyme immunoassay.