Table 3

ORs for COVID-19 requiring mechanical ventilation by cardiometabolic factors and other comorbidities

Risk factorsAdjusted for age and sexAdjusted model 2*Adjusted model 3 †
OR95% CIP valueOR95% CIP valueOR95% CIP value
Type 1 diabetes2.321.12 to 4.810.0233.131.52 to 6.420.0022.561.25 to 5.240.010
Type 2 diabetes2.732.33 to 3.20<0.0012.251.90 to 2.65<0.0011.811.49 to 2.19<0.001
Obesity3.232.56 to 4.08<0.0013.132.43 to 4.02<0.0012.031.55 to 2.65<0.001
Hypertension1.761.52 to 2.05<0.0011.731.48 to 2.01<0.0011.261.05 to −1.51<0.013
Hyperlipidaemia1.351.15 to 1.58<0.0011.221.03 to 1.43<0.0180.900.75 to 1.090.286
CKD2.831.97 to 4.05<0.0012.511.69 to 3.70<0.0011.841.21 to 2.820.005
CVD1.070.86 to 1.330.5541.030.82 to 1.290.7890.750.58 to 0.960.022
Heart failure1.230.87 to 1.730.2361.130.79 to 1.620.480.780.51 to 1.190.253
Atrial fibrillation1.110.85 to 1.460.431.240.93 to 1.640.1361.040.75 to 1.430.819
VTE1.741.27 to 2.390.0011.901.37 to 2.62<0.0011.651.18 to 2.310.004
COPD1.370.94 to 1.990.1051.340.91 to 1.970.1330.870.56 to 1.360.552
Asthma2.842.26 to 3.58<0.0012.782.18 to 3.53<0.0012.251.74 to 2.90<0.001
Malignancy0.890.74 to 1.060.1950.970.80 to 1.170.7250.850.70 to 1.040.103
Rheumatoid arthritis1.791.06 to 3.000.0291.861.11 to 3.120.0191.270.72 to 2.230.407
Systemic inflammatory disease2.651.79 to 3.92<0.0012.571.71 to 3.86<0.0011.961.28 to 2.990.002
Inflammatory bowel disease1.070.65 to 1.770.7921.210.72 to 2.030.4790.940.54 to 1.640.839
  • *Adjusted for age, sex, educational level, marital status and region of birth.

  • †Adjusted for age, sex, educational level, marital status and region of birth and all diagnoses in table 3.

  • CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVD, cardiovascular disease; VTE, venous thromboembolism.