Description of the instruments used for the evaluation of all patients
| Instrument | Description | Domains/subscales | Score |
| MoCA31 35 | Test for the rapid screening of mild cognitive impairment—an intermediate clinical state between normal cognitive ageing and dementia. | Attention and concentration; executive functions; memory; language; visuoconstructional skills; calculations; orientation. | Range: 0–30 |
| Higher scores represent better cognitive performance. | |||
| Cube Test33 | A two-task cognitive screening tool that consists in completing a 3D cube from six pieces (task 1) and remembering the position of the six pieces on a grid with 25 squares measuring eight by eight centimeters from a previously shown scheme (task 2). | Visuoconstructional skills; executive function; processing speed; delayed memory. | Time to construct the first vertex and to complete cube and the number of pieces correctly assembled in up to 6 min (task 1); number of pieces correctly positioned on the grid (task 2). |
| Brain on Track34 | A self-administered computerised test intended for longitudinal cognitive testing that includes eight subtests. | Attention; memory; executive functions; language; calculation; constructive ability; visuospatial processing. | Range: virtually unlimited (maximum number of correct answers in a fixed time) |
| Higher scores represent better cognitive performance. | |||
| Scores falling below an expected performance threshold for each age/education group; a pattern of decline in individual performance. | |||
| HADS21 22 | Scale with 14 questions assessing anxiety and emotional distress among patients during the previous week. | Depression; anxiety. | Range (for each subscale): 0 to 21 |
| Scores greater than or equal to 11 represent a case of anxiety or depression, as applicable. | |||
| PSQI23 24 | Index with 18 questions assessing sleep quality and disturbances during the previous month. | Subjective sleep quality; sleep latency; duration of sleep; habitual sleep efficiency; sleep disorders; use of medications for sleep; daytime dysfunction. | Range: 0–21 |
| Scores greater than five indicate poor sleep quality. | |||
| QLQ-C3025 26 | Scale with 30 questions assessing quality of life in patients with cancer during the previous week. | Global health status. | Range (scales and single-item): 0–100 |
| Functional scales: physical functioning; role functioning; emotional functioning; cognitive functioning; social functioning. | Higher scores for the global health status and for a functional scale represent a healthy level of quality of life and functioning, respectively. | ||
| Symptom scales/items: fatigue; nausea and vomiting; pain; dyspnoea; insomnia; appetite loss; constipation; diarrhoea; financial difficulties. | Higher scores for a symptom scale/item represents a higher level of symptomatology/ problems. | ||
| QLQ-PR2527 | Specific Prostate Cancer Scale with 25 questions assessing quality of life in patients with prostate cancer during the previous week and the last 4 weeks. | Functional scales: sexual activity; sexual functioning. | Range (scales and single-item): 0 to 100 |
| Symptom scales: urinary symptoms; bowel symptoms; hormonal treatment-related symptoms; incontinence aid. | Higher scores for a function scale/item reflect a healthy level of functioning. | ||
| Higher scores for a symptom scale/item reflect a higher level of symptomatology/problems. | |||
| EQ-5D-5L28 | A measure of health-related quality of life with five questions and a Visual Analogue Scale. | Mobility, self-care, usual activities, pain/discomfort; anxiety/depression and a visual analogue scale. | A total of 3125 possible health states are defined to describe the patient’s health state. Each state is referred to in terms of a 5-digit code. |
| Vertical Visual Analogue Scale | |||
| Range: 0–100 | |||
| Higher scores reflect ‘The best health you can imagine’ and lower scores reflect ‘The worst health you can imagine’. | |||
| METER29 30 | A measure of health literary including 40 words and 30 non-words. | 40 words and 30 non-words. | Range: 0–40 and 0–30 |
| Adequate health literacy is defined as scoring at least 35/40 in words and 18/30 in non-words. |
3D, three dimensions; EQ-5D-5L, Measure of health-related quality of life of the EuroQol Group; HADS, Hospital Anxiety and Depression Scale; METER, Medical Term Recognition Test; MoCA, Montreal Cognitive Assessment; PSQI, Pittsburgh Sleep Quality Index; QLQ-C30, Quality of Life Questionnaire of the European Organisation for Research and Treatment of Cancer; QLQ-PR25, Prostate cancer-specific module of the Quality of Life Questionnaire of the European Organisation for Research and Treatment of Cancer.