Table 1

Summary of the timeline of collection of the outcome measures

PhaseTimelineOutcome categoryOutcome measures
Pre-interventionWeek 0 day 1Primary (imaging)MRI
Primary (experimental)Day 1 medium-transfer tasks*
Primary (clinical)Clinical measures†
ControlDemographics, mood‡
Week 0 day 2Primary (experimental)Day 2 medium-transfer tasks§
Far-transfer tasks¶
ControlPhysical activity**
InterventionWeeks 1–16, days 1–5Primary (experimental)Near-transfer tasks††
Secondary (feasibility)Compliance to intervention‡‡
Weeks 1–16, day 5 onlySecondary (feasibility)How Much Is Too Much Scale
Post-interventionWeek 17 day 1Primary (imaging)MRI
Primary (experimental)Day 1 medium-transfer tasks*
Primary (clinical)Clinical measures†
ControlPhysical activity**
Week 17 day 2Primary (experimental)Day 2 medium-transfer tasks§
Far-transfer tasks¶
Secondary (feasibility)Semistructured interview
Week 17 days 1–5Primary (experimental)Near-transfer tasks‡‡
  • *Tasks include Different Approach Task, Path Integration Task.

  • †Digit Span, Visual Spatial Span, SART, Symbol Digit Modalities Test, flanker inhibitory control and attention test, dimensional change card sort test, pattern comparison processing speed test, picture sequence memory test, RAVLT, RVDLT, GOSE.

  • ‡Age, sex, injury severity, hours of therapy, BAI, BDI.

  • §CMFT, SBSOD, NSQ.

  • ¶MIC, MST, EMQ.

  • **IPAQ.

  • ††Training-related outcome measures, and comparison of performance on week 1 and untrained city (week 17) for navigation participants only.

  • ‡‡Whether at least 80% of intervention has been completed, and average percentage of daily tasks completed.

  • BAI, Beck Anxiety Inventory; BDI, Beck Depression Inventory; CMFT, Cognitive Map Formation Test; EMQ, Everyday Memory Questionnaire; GOSE, Glasgow Outcome Scale Extended; IPAQ, International Physical Activity Questionnaire; MIC, Memory Image Completion Task; MST, Mnemonic Similarity Test; NSQ, Navigational Strategies Questionnaire; RAVLT, Rey Auditory Verbal Learning Test; RVDLT, Rey Visual Design Learning Test; SART, Sustained Attention to Response Test; SBSOD, Santa Barbara Sense of Direction Scale.