Comparison of available first-round performance indicators in organised FIT programmes in Europe18 20 29
Denmark 2014–2017 | Finland 2019 | Italy 2013 | The Netherlands 2014 | Slovenia 2011–2012 | Spain 2013 | |||||||||||||
60–69 years | 60–66 years | 60–69 years | 60, 63, 65 and 67 years | 60–69 years | 60–69 years | |||||||||||||
20 µg Hg/g faeces | 25 and 70 µg Hg/g faeces | 20 µg Hg/g faeces | 15 and 47 µg Hg/g faeces | 20 µg Hg/g faeces | 20 µg Hg/g faeces | |||||||||||||
Men | Women | All | Men | Women | All | Men | Women | All | Men | Women | All | Men | Women | All | Men | Women | All | |
Participation* | 63.5 | 70.3 | 67.0 | 74.7 | 83.4 | 79.3 | 46.5 | 49.7 | 48.2 | 72.0 | 76.0 | 74.0 | 56.0 | 63.4 | 59.9 | 50.9 | 53.9 | 52.5 |
Positivity† | 9.4 | 6.0 | 7.6 | 2.8 | 2.4 | 2.6 | 8.8 | 6.1 | 7.4 | 7.9 | 4.9 | 6.4 | 12.1 | 7.2 | 9.6 | 11.5 | 7.0 | 9.1 |
PPV test for CRC‡ | 5.9 | 5.0 | 5.5 | 6.6 | 6.4 | 6.5 | 4.8 | 3.4 | 4.2 | 5.9 | 5.6 | 5.8 | 6.5 | 3.8 | 5.5 | 7.3 | 4.4 | 6.1 |
PPV test for AA§ | NA | NA | NA | 25.7 | 15.5 | 20.4 | 17.3 | 11.3 | 14.7 | 34.0 | 27.3 | 31.4 | 39.6 | 24.3 | 33.8 | 44.1 | 27.3 | 37.3 |
PPV test for A¶ | 46.3 | 36.2 | 42.0 | 44.1 | 34.8 | 39.3 | 31.2 | 21.3 | 26.9 | 50.3 | 41.7 | 46.9 | 57.1 | 37.5 | 49.6 | 59.2 | 42.4 | 52.4 |
PPV colonoscopy for CRC** | 6.6 | 5.6 | 6.2 | 9.1 | 8.8 | 8.9 | 7.1 | 5.4 | 6.4 | 7.4 | 7.2 | 7.3 | 7.6 | 4.3 | 6.3 | 8.0 | 4.9 | 6.7 |
PPV colonoscopy for AA†† | NA | NA | NA | 34.8 | 21.3 | 27.8 | 25.7 | 17.9 | 22.4 | 42.7 | 35.1 | 39.8 | 45.8 | 27.7 | 38.8 | 48.5 | 30.2 | 41.1 |
PPV colonoscopy for A‡‡ | 51.3 | 40.8 | 47.0 | 59.7 | 47.7 | 53.5 | 46.5 | 33.7 | 41.2 | 63.2 | 53.6 | 59.5 | 66.1 | 42.7 | 57.0 | 65.0 | 47.0 | 57.8 |
CRC detection rate§§ | 5.6 | 3.0 | 4.2 | 1.8 | 1.6 | 1.7 | 4.2 | 2.0 | 3.1 | 4.6 | 2.8 | 3.7 | 7.9 | 2.7 | 5.3 | 8.4 | 3.1 | NA |
AA detection rate¶¶ | NA | NA | NA | 7.2 | 3.8 | 5.3 | 15.2 | 6.8 | 10.8 | 26.9 | 13.4 | 20.0 | 48.1 | 17.5 | 32.4 | 50.8 | 19.1 | 34.1 |
A detection rate*** | 43.6 | 21.7 | 31.9 | 12.3 | 8.4 | 10.2 | 27.4 | 12.9 | 19.8 | 39.7 | 20.4 | 29.9 | 69.0 | 27.0 | 52.5 | 68.2 | 29.7 | 47.9 |
*The proportion of persons returning the stool sample out of those invited.
†The proportion of participating persons with a test result at or above the cut-off level out of those with an assessable stool sample.
‡The proportion of persons with CRC out of those with a positive test result.
§The proportion of persons with AA out of those with a positive test result.
¶The proportion of persons with any adenoma out of those with a positive test result.
**The proportion of persons with CRC out of those who underwent a colonoscopy.
††The proportion of persons with AA out of those who underwent a colonoscopy.
‡‡The proportion of persons with any adenoma out of those who underwent a colonoscopy.
§§The proportion of persons with CRC out of those with an assessable stool sample.
¶¶The proportion of persons with AA out of those with an assessable stool sample.
***The proportion of persons with any adenoma out of those with an assessable stool sample.
A, adenoma; AA, advanced adenoma; CRC, colorectal cancer; FIT, faecal immunochemical test; NA, not available; PPV, positive predictive value.