Table 4

Estimated differences in costs ($A) and patient deaths from current practice versus WGS surveillance

20212022202320242025
Current practice
 Total number of patients expected to have MRO infections/colonisation97 53992 80988 07983 34978 619
 Cost of microbiology screening$8 028 283$7 638 967$7 249 651$6 860 335$6 471 019
 Cost of cleaning and nursing time$11 911 230$11 333 618$10 756 006$10 178 394$9 600 782
 Cost of extra length of stay$44 793 430$45 297 162$45 800 893$46 304 625$46 808 356
 Cost of PPE$91 162 386$87 836 074$84 509 762$81 183 450$77 857 139
 Cost of antibiotic treatment of patients$14 952 034$14 152 425$13 352 816$12 553 207$11 753 598
 Total cost: current practice$170 847 364$166 258 246$161 669 129$157 080 012$152 490 895
 Expected number of patient deaths20321982193218811831
WGS surveillance
 Total number of potentially avoided infections with WGS (patients)20852003192118391757
 Total number of potentially avoided colonisations with WGS (patients)34 64132 28729 93427 58025 227
 Total number of potentially avoided infected/colonised with WGS36 72634 29031 85529 41926 984
 Cost of WGS$26 575 746$25 573 072$24 570 397$23 567 723$22 565 049
 Cost of cleaning and nursing time$7 426 340$7 146 152$6 865 964$6 585 777$6 305 589
 Cost of extra length of stay$36 149 780$36 881 764$37 613 748$38 345 732$39 077 716
 Cost of PPE$60 703 607$59 267 592$57 831 577$56 395 563$54 959 548
 Cost of treating infected patients$9 123 437$8 713 828$8 304 219$7 894 610$7 485 001
 Total cost: WGS surveillance$139 978 910$137 582 408$135 185 906$132 789 404$130 392 902
 Expected number of patient deaths13821369135613421329
Cost savings with WGS surveillance$30 868 454$28 675 839$26 483 223$24 290 608$22 097 992
Patient deaths avoided650613576539502
Costs saved per avoided infection−$14 805−$14 317−$13 787−$13 210−$12 579
Costs saved per avoided colonisation−$891−$888−$885−$881−$876
  • MRO, multidrug-resistant organism; PPE, personal protective equipment; WGS, whole-genome sequencing.