Table 1

Baseline description of demographic and clinical characteristics of two cohorts of patients presenting between 1995–1999 and 2005–2016 for assessment of first-episode psychosis prior to (C1) and after (C2) the introduction of an EIP service

C1 (1995–1999)
n=171
C2 (2005–2016)
n=319
Gender, n (%)
 Male99 (58)189 (59.2)
 Female72 (42)130 (40.8)
Age, mean (SD)28.5 (11.1)32.5 (11.3)
Inpatient on assessment, n (%)144 (84.2)216 (67.7)
Initial diagnosis*, n (%)
 Schizophrenia spectrum101 (59.1)124 (39.2)
 Substance-induced psychosis12 (7)45 (14.2)
 Major depressive disorder11 (6.4)36 (11.4)
 Bipolar disorder25 (14.6)35 (11.1)
 Delusional disorder13 (7.6)35 (11.1)
 Brief psychotic disorder022 (7)
 All other psychotic diagnoses4 (5.2)19 (6)
MeanMedianRangeMedian (IQR)
DUP (months)†17.950.25–2403 (0.63–13)
GAF‡22.935 (30–48.5)
PANSS-Total74.4
PANSS-Negative15.7
PANSS-Positive21.3
SAPS-Total§18 (10–31)
SANS-Total¶12 (3–22)
  • *3 missing C2.

  • †5 missing C1; 156 missing C2.

  • ‡6 missing C2.

  • §11 missing C2.

  • ¶14 missing C2.

  • DUP, estimated duration of untreated psychosis; EIP, early intervention in psychosis; GAF, Global Assessment of Functioning; PANSS-Negative, Positive and Negative Syndrome Scale negative symptom score; PANSS-Positive, Positive and Negative Syndrome Scale positive symptom score; PANSS-Total, Positive and Negative Syndrome Scale total symptom score; SANS-Total, Scale for the Assessment of Negative Symptoms total score; SAPS-Total, Scale for the Assessment of Positive Symptoms total score.