Description of studies that reported the number of participants that experienced adverse effects and dropped out due to adverse effects (n=4)
| Authors (year) | Groups | No of participants with adverse effects/total (%) | No of participants that dropped out |
| Studer et al 201229 | Midazolam 7.5 mg | 6/12 (50.0) | 0 |
| Clonidine 150 μg | 5/12 (41.6) | ||
| Rodrigo and Cheung22 1987 | Midazolam 15 mg | 17/30 (56.6) | 0 |
| Placebo | 9/30 (30.0) | ||
| Manani et al 197921 | Trazodone 25 mg | 12/20 (60.0) | 0 |
| Trazodone 50 mg | 11/21 (52.3) | ||
| Pinheiro et al 201430 | Valeriana officinalis 100 mg | 9/10 (90.0) | 0 |
| Placebo | 7/10 (70.0) |