Table 5

Summary of risk factors of severe neonatal jaundice

NICEMaHTASQCGINSAAPTPANPAISNSAPSSNCPSChPS
Maternal
Blood group ONA++++NANANANANA+NA
Rhesus negative+++++NANANANANA+NA
DiabetesNA++NA+NANANANANANANA
Neonatal
G6PD deficiency++++++NANA+NA++
Under 38 weeks+++NA++NANA+NA++
Exclusive breastfeeding+++NA+NANANA+NA++
Cephalhaematoma or bruises++NA+NANANA+NA++
Sepsis+++NA++NANA+NA+
Sibling with severe hyperbilirubinemiaNA+NA+NANANANANANA+NA
Sibling with clinically significant jaundice requiring phototherapy+NA+NA+NANANANANANANA
Visible jaundice at younger than 24 hours++NA++NANANANANA+NA
MaleNA+NA+NANANANANA+NA
  • AAP, American Academy of Pediatrics Subcommittee on Hyperbilirubinemia (America); ChPS, Chinese Pediatric Society, Chinese Medical Association (China); CPS, Canadian Pediatric Society, Fetus and Newborn Committee (Canada); G6PD, Glucose-6-phosphate dehydrogenase; INS, Israel Neonatal Society (Israel); ISN, Italian Society of Neonatology (Italy); MaHTAS, Malaysia Health Technology Assessment Section (Malaysia); NA, not available; NICE, National Institute for Health and Care Excellence (the UK); NPA, Norwegian Pediatric Association (Norway); QCG, Queensland Clinical Guidelines (Australia); SAP, Spanish Association of Pediatrics (Spain); SSN, Swiss Society of Neonatology (Swiss); TPA, Turkish Pediatric Association (Turkey).