0 hour | 1 hour | 24 hours | 48 hours | 72 hours | |
A. Laboratory parameters assessed at different time points during the study. The parameters from 0 hour will be taken from clinical routine measurements before initiation of V-V ECMO | |||||
Leukocytes (thous./µL) | × | × | × | × | × |
Thrombocytes (thous./µL) | × | × | × | × | × |
Haemoglobin (g/dL) | × | × | × | × | × |
Haematocrit (%) | × | × | × | × | × |
Lymphocytes (thous./µL) | × | × | × | × | × |
Neutrophils (thous./µL) | × | × | × | × | × |
Monocytes (thous./µL) | × | × | × | × | × |
INR (international normalized ratio) | × | × | × | × | × |
PTT (s) (partial thromboplastin time) | × | × | × | × | × |
D-dimers (mg/L) | × | × | × | × | × |
Fibrinogen (Clauss method) (mg/dL) | × | × | × | × | × |
Willebrand factor acitivity (%) | × | × | × | × | × |
Willebrand factor antigene (%) | × | × | × | × | × |
Ferritin (ng/mL) | × | × | × | × | × |
Urea (mg/dL) | × | × | × | × | × |
Creatinine (mg/dL) | × | × | × | × | × |
Uric acid (mg/dL) | × | × | × | × | × |
LDH (U/L) (lactate dehydrogenase) | × | × | × | × | × |
CK (U/L) (creatine kinase) | × | × | × | × | × |
CK-MB (U/L) (creatine kinase, MB isoenzyme) | × | × | × | × | × |
Myoglobin (U/L) | × | × | × | × | × |
Troponin T (ng/mL) | × | × | × | × | × |
NT-proBNP (pg/mL) (aminoterminal form brain natriuretic peptide) | × | × | × | × | × |
AST (U/L) (aspartate aminotransferase) | × | × | × | × | × |
ALT (U/L) (alanine aminotransferase) | × | × | × | × | × |
AP (U/L) (alkaline phosphatase) | × | × | × | × | × |
g-GT (U/L) (gamma-glutamyltransferase) | × | × | × | × | × |
Bilirubin (mg/dL) | × | × | × | × | × |
CRP (mg/L) (C-reactive protein) | × | × | × | × | × |
PCT (ng/mL) (procalcitonin) | × | × | × | × | × |
Total serum protein (g/dL) | × | × | × | × | × |
Albumin (g/dL) | × | × | × | × | × |
IL-6 (pg/mL) (interleukin-6) | × | × | × | × | × |
Triglycerides (mg/dL) | × | × | × | × | × |
Cholesterine (mg/dL) | × | × | × | × | × |
LDL-cholesterine (mg/dL) (low-density lipopotein cholesterine) | × | × | × | × | × |
HDL-cholesterine (mg/dL) (high-density lipoprotein cholesterine) | × | × | × | × | × |
B. Point-of-care tests collected during the study. The parameters from 0 hour will be taken from clinical routine measurements before initiation of V-V ECMO | |||||
pH | × | × | × | × | × |
pCO2 (mm Hg) (partial pressure of carbon dioxide) | × | × | × | × | × |
pO2 (mm Hg) (partial pressure of oxygen) | × | × | × | × | × |
sO2 (%) (oxygen saturation) | × | × | × | × | × |
SBC (mmol/L) (standard bicarbonate) | × | × | × | × | × |
Lactate (mmol/L) | × | × | × | × | × |
Sodium (mmol/L) | × | × | × | × | × |
Potassium (mmol/L) | × | × | × | × | × |
Chloride (mmol/L) | × | × | × | × | × |
Calcium (mmol/L) | × | × | × | × | × |
thous, thousand; V-V ECMO, veno-venous extracorporeal membrane oxygenation.