Table 2

Determinants for incorrect use of the clinical prediction rule in patients suspected of VTE

VariableAll patients*,
n=1477,
n (%)
Correct CPR,
n=1138
n (%)
Incorrect CPR, n=339,
n (%)
Univariable analysis,
OR (95% CI)
Multivariable analysis†,
OR (95% CI)
Age (years)
 ≤50543 (36.8)403 (35.4)140 (41.3)11
 >50 and ≤75651 (44.1)516 (45.3)135 (39.8)0.75 (0.58 to 0.99)0.71 (0.54 to 0.94)
 >75283 (19.2)219 (19.2)64 (18.9)0.84 (0.60 to 1.18)0.75 (0.53 to 1.07)
Sex
 Men578 (39.1)712 (62.6)187 (55.2)11
 Women899 (60.9)426 (37.4)152 (44.8)0.74 (0.58 to 0.94)0.69 (0.54 to 0.89)
Heart failure
 No1449 (98.1)1123 (98.7)326 (96.2)11
 Yes28 (1.9)15 (1.3)13 (3.8)2.99 (1.41 to 6.34)3.26 (1.47 to 7.21)
COPD/asthma
 No1307 (88.5)1018 (89.5)289 (85.3)11
 Yes170 (11.5)120 (10.550 (14.7)1.47 (1.03 to 2.09)1.38 (0.95 to 2.01)
Active malignancy
 No1380 (93.9)1066 (94.1)314 (93.5)11
 Yes89 (6.1)67 (5.9)22 (6.5)1.11 (0.68 to 1.83)1.11 (0.67 to 1.86)
Recent surgery/ immobilisation
 No1369 (93.1)1063 (93.7)306 (91.1)11
 Yes101 (6.9)71 (6.3)30 (8.9)1.47 (0.94 to 2.29)1.57 (1.00 to 2.47)
Previous VTE‡
 No386 (80.1)304 (86.9)82 (62.1)11
 Yes96 (19.9)46 (13.1)50 (37.9)4.03 (2.52 to 6.44)4.45 (2.73 to 7.25)
  • *Data were missing for the following variables: active malignancy (two patients), recent surgery or immobilisation (seven patients) and previous VTE (two patients).

  • †Due to missing data in 10 individual patients, 1467 patients were included in the multivariable analysis.

  • ‡Results based only on 482 patients with suspected PE.

  • COPD, chronic obstructive pulmonary disease; CPR, clinical decision rule; PE, pulmonary embolism; VTE, venous thromboembolism.