Table 1

Zika virus infections and CZS cases reported to PAHO/WHO by countries in the South and Central Americas, Mexico and the Caribbean, 2016 – 2017* and the estimated number of CZS cases per 1000 births to pregnant women with Zika virus

Country	Zika virus infections†						CZS		Population (’000) in 2016/17	Annual births in 2016/17‡
Country	Suspected	Confirmed (including imported)	% Suspected	Total suspected and confirmed	Incidence of Zika virus (suspected and confirmed) per 1000 people per year	Incidence of Zika virus (confirmed) per 1000 people per year	CZS cases	CZS per 1000 births (2016/17)	Population (’000) in 2016/17	Annual births in 2016/17‡
	A	B		A+B	(A+B)/2D	B/2D	C	C/2E×1000	D	E
Brazil*	205 997	155 820	56	361 817	0.86	0.372	2952	0.507	209 428	2 911 930
Colombia	100 255	9717	91	109 972	1.13	0.099	248	0.190	48 860	652 112
Guatemala	4003	1054	79	5057	0.15	0.031	140	0.181	16 793	386 023
Dominican Republic	5248	336	93	5584	0.26	0.015	85	0.296	10 708	143 822
Puerto Rico	–	36 871	0	36 871	10.02	10.016	47	0.892	1840	26 357
Mexico	–	11 791	0	11 791	0.05	0.045	20	0.004	128 897	2 263 873
Costa Rica	21	9949	0	9970	1.02	1.019	19	0.137	4881	69 410
Panama	4786	1059	81	5845	0.72	0.130	17	0.113	4044	75 008
Trinidad and Tobago	–	722	0	722	0.26	0.264	17	0.475	1367	17 883
Ecuador	3722	3011	55	6733	0.20	0.091	14	0.025	16 505	283 020
Bolivia	2216	816	73	3032	0.14	0.037	14	0.027	10 970	255 713
Honduras	31 378	266	99	31 644	1.81	0.015	8	0.022	8727	184 312
Martinique	37 997	–	100	37 997	48.65	0.000	5	0.674	390	3711
Guadeloupe	32 250	28	99	32 278	35.05	0.030	5	0.570	460	4389
Argentina	536	276	66	812	0.01	0.003	5	0.003	44 059	716 322
El Salvador	12 467	3	99	12 470	1.00	0.000	4	0.018	6262	109 617
Suriname	2816	733	79	3549	3.19	0.659	4	0.203	555	9847
Guyana	–	34	0	34	0.04	0.044	3	0.115	385	13 060
Nicaragua	751	614	55	1365	0.11	0.049	2	0.007	6184	137 772
Grenada	335	119	73	454	2.04	0.533	2	0.672	111	1487
Paraguay	106	14	88	120	0.01	0.001	2	0.008	6768	128 117
French Guiana	10 742	48	99	10 790	19.30	0.085	1	0.065	279	7663
Haiti	3077	–	100	3077	0.28	0.000	1	0.002	5424	247 025
Saint Martin	1580	200	88	1780	55.63	6.250	1	1.000	16	500
Barbados	672	137	83	809	1.39	0.234	1	0.196	291	2552
Venezuela	61 708	–	100	61 708	0.97	0.000	0	0	31 748	602 123
Jamaica	6958	186	97	7144	1.25	0.032	0	0	2846	35 164
Peru	5737	1293	81	7030	0.11	0.020	0	0	31 969	502 591
Curacao	4362	2020	68	6382	21.27	6.733	0	0	150	1668
Belize	1762	269	86	2031	2.74	0.362	0	0	371	7200
Cuba	1305	324	80	1629	0.07	0.014	0	0	11 439	115 921
Aruba	830	645	56	1475	6.44	2.816	0	0	114	1230
Dominica	1154	79	93	1233	8.33	0.533	0	0	74	721
Saint Vincent and the Grenadines	505	84	85	589	5.77	0.823	0	0	51	1634
Saint Kitts and Nevis	554	33	94	587	5.59	0.314	0	0	52	641
Antigua and Barbuda	537	25	95	562	2.97	0.132	0	0	94	1085
Bahamas	510	25	95	535	0.68	0.031	0	0	394	4055
Virgin Islands (USA)	400	56	87	456	4.43	0.543	0	0	51	1415
Sint Maarten	248	148	62	396	4.77	1.783	0	0	41	363
Saint Lucia	280	52	84	332	1.01	0.158	0	0	164	2103
Saint Barthelemy	270	61	81	331	36.78	6.777	0	0	4	72
Cayman Islands	229	30	88	259	2.25	0.260	0	0	57	642
Turks and Caicos Islands	197	25	88	222	2.13	0.240	0	0	52	518
Virgin Islands (UK)	74	53	58	127	1.84	0.768	0	0	34	266
Anguilla	30	23	56	53	1.56	0.676	0	0	17	155
Montserrat	18	5	78	23	2.30	0.500	0	0	5	46
Bonaire, St Eustatius and Saba	–	9	0	9	0.35	0.346	0	0	13	346
Total	548 623	239 063	70	787 686			3617

1. Brazil Ministry of Health case definition for confirmed cases of congenital syndrome associated with Zika virus infection includes confirmed and probable cases per PAHO’s case definition.
2. The number of confirmed congenital syndrome associated with Zika include two autochthonous cases and three imported cases.
3. The reported number of suspected cases of Zika virus infection are estimates. According to Santé publique France, the estimated number of suspected cases is the sum of the number of visits recorded by the Decentralised Centres of Prevention and Care and the estimated number of people who sought medical care from a general practitioner for this purpose. The estimate is based on data collected by the sentinel physician network.
4. The case reported by Santé publique France corresponds to a fetus with cerebral malformation of a mother infected with Zika.
5. In addition to the five reported cases of congenital syndrome, Santé publique France reported 16 fetuses with cerebral malformations of mothers infected with Zika.
6. Santé publique France reported 21 fetuses with cerebral malformations of mothers infected with Zika.
7. In addition to the one reported case of congenital syndrome, Santé publique France reported 18 fetuses with cerebral malformations of mothers infected with Zika.
*CZS cases in Brazil occurring in 2015 are included.
†PAHO/WHO case definitions for suspected and confirmed Zika virus infections is available at: http://www.paho.org/hq/index.php?option=com_content&view=article&id=11117&Itemid=41532&lang=en.
‡Total births were estimated as twice the most recent birth years if data were not available for 2016 and 2017: Honduras (2012), Haiti (2013), Grenada (2014), Trinidad and Tobago (2015), El Salvador (2015) and Guyana (2015).
§Confirmed congenital syndrome associated with Zika virus infection case definition: live newborn who meets the criteria for a suspected case of congenital syndrome associated with Zika virus and Zika virus infection was detected in specimens of the newborn, regardless of detection of other pathogens. Case definitions for congenital syndrome associated with Zika virus infection is available at: http://www.paho.org/hq/index.php?option=com_content&view=article&id=11117&Itemid=41532&lang=en.
CZS, congenital Zika syndrome; PAHO, Pan American Health Organization.