Table 4

Risk of all-cause mortality for individual index conditions in patients with rheumatoid arthritis (RA) and no index condition, RA with index condition, RA with no index condition and RA and index condition

Risk of all-cause mortality
No RA, no index conditionNo RA, with index condition HR (95% CI)RA, no index condition HR (95% CI)RA and index condition HR (95% CI)
Index condition
 Hypertension11.24 (1.21 to 1.28)1.29 (1.11 to 1.48)1.59 (1.37 to 1.86)
 Coronary heart disease11.57 (1.50 to 1.65)1.26 (1.12 to 1.42)2.07 (1.63 to 2.63)
 Diabetes11.68 (1.60 to 1.75)1.33 (1.18 to 1.48)1.83 (1.37 to 2.44)
 Asthma11.10 (1.05 to 1.15)1.27 (1.13 to 1.42)1.56 (1.22 to 2.00)
 Dyspepsia11.01 (0.97 to 1.06)*1.27 (1.14 to 1.43)1.45 (1.10 to 1.90)
 Cancer12.50 (2.41 to 2.59)1.35 (1.20 to 1.52)3.04 (2.39 to 3.86)
 Depression11.27 (1.20 to 1.35)1.29 (1.15 to 1.44)1.71 (1.21 to 2.42)
 Thyroid disorder11.05 (0.98 to 1.12)*1.32 (1.18 to 1.47)1.14 (0.80 to 1.62)*
 COPD12.11 (1.98 to 2.49)1.26 (1.13 to 1.42)2.68 (2.00 to 3.58)
 Epilepsy11.81 (1.42 to 1.82)1.29 (1.15 to 1.43)2.86 (1.43 to 5.73)
 Migraine10.85 (0.76 to 0.94)1.29 (1.16 to 1.44)1.09 (0.55 to 2.19)*
 Psoriasis/eczema11.05 (0.98 to 1.14)*1.27 (1.14 to 1.42)1.88 (1.20 to 2.95)
 Prostate disease10.83 (0.76 to 0.90)1.30 (1.17 to 1.45)0.90 (0.43 to 1.90)*
 Osteoporosis11.26 (1.14 to 1.39)1.25 (1.12 to 1.40)2.20 (1.55 to 3.12)
 Atrial fibrillation11.40 (1.45 to 1.57)1.30 (1.17 to 1.45)1.32 (0.50 to 3.52)*
 Anxiety11.22 (1.10 to 1.35)1.30 (1.16 to 1.44)1.48 (0.67 to 3.30)*
 Inflammatory bowel disease11.37 (1.20 to 1.57)1.30 (1.17 to 1.44)1.30 (0.54 to 3.11)*
 Heart failure12.69 (2.22 to 3.25)1.29 (1.16 to 1.43)5.14 (2.14 to 12.38)
  • Age-adjusted Cox’s proportional hazards models were adjusted for sex, Townsend score, smoking status, alcohol intake frequency, body mass index, physical activity level and rheumatoid factor status. Cox’s proportional hazards p<0·01, except for those labelled with *indicating p>0.01. Index conditions labelled ** have interaction term p<0.01.

  • COPD, Chronic Obstructive Pulmonary Disease.