Table 3

Distribution of countries or regions of recruitment per study for registered studies sponsored by China and global registrations up to 2018

YearChina (N=32 557)Global (N=450 194)
One country/regionMRCTsOne country/regionMRCTs
Pre-2009700472 40013 527
2009626420 6732934
2010785322 7362956
20111199124 0983012
20121755627 9193224
20132072329 7502841
20142675532 6493107
201532201334 8423238
201645841340 3023162
201761981246 2872999
201886212154 6372901
TOTAL (n/%)32 435 (99.6)122 (0.4)406 293 (90)43 901 (10)
TrialsRecruitment countries or regions per trial of MRCTs (n/%)
Two countries/regions3–56–10>11
China69 (57)23 (19)15 (12)15 (12)
Global12 804 (29)12 722 (29)9239 (21)9136 (21)
  • Data note: There were 1932 registered studies sponsored by China with absent recruitment countries/regions data, and the recruitment country/region was assigned to China after manual verification. Another 28 067 registration entries with absent recruitment countries/regions data were excluded from the analysis because the missing recruitment countries/regions could not be determined manually. In addition, 407 registration entries on Japan Primary Registries Network only specified the continents of recruitment. The number of recruitment continents was used to represent the number of recruitment countries or regions in these entries.

  • MRCTs, multiregional clinical trials.