Table 1

Schedule of data collection

Data itemPrerandomisationPresurgeryIntra
operative		Postsurgery (until discharge)Discharge4 weeks post surgery4 months post surgery
Sociodemographic details✓     
Comorbidities✓     
Routine clinical measures✓  ✓ 
Resource use schedule   ✓✓✓
SF-12✓   ✓✓
EQ-5D 5L✓   ✓✓
BPI✓   ✓✓
NRS pain score✓* ✓*✓ 
Study medication✓✓†  
Opioid use✓✓✓✓✓✓
Adverse events  ✓✓ 
Serious adverse events  ✓✓✓✓

  • *Routinely collected NRS pain scores as close as possible to the following time points may be used: prerandomisation, 1 hour, 4 hours, 12 hours postsurgery and two times per day postsurgery until discharge. NRS pain assessments will not be possible in intubated patients.

  • †Study medication given morning and evening for 2 days following extubation (where applicable).

  • BPI, brief pain inventory; NRS, numerical rating scale.