Table 2

Base case clinical outcomes for model comparing universal repeat screening of syphilis in late pregnancy with single screening

Screening strategySyphilis antenatal screensWomen treated for syphilisFalse positive maternal syphilisIntrauterine fetal demise (all causes)*Preterm deliveries (all causes)*Neonatal deaths (all causes)*Congenital syphilis cases
Existing: single screen
Estimate725 891170514512904.454 2281446.58.8
95% CI†725 891 to 725 8911698 to 17371443 to 14822890 to 291653 905 to 54 2821441 to 14578.7 to 8.9
Alternative: repeat screen
Estimate1 411 696308928232904.154 2261446.43.3
95% CI†1 411 456 to 1 411 5033074 to 31502806 to 28832889 to 291553 903 to 54 2801441 to 14573.3 to 3.3
Difference685 80513841372−0.3−2−0.1−5.5
  • *These adverse pregnancy outcomes are all-cause outcomes for all 725 891 women screened, including the small number with syphilis infection.

  • †95% confidence interval, calculated using probabilistic sensitivity analysis.