Base case short-term annual healthcare costs from model comparing universal repeat screening of syphilis in late pregnancy with single screening
| Screening strategy | Total healthcare costs | Cost breakdown* | ||
| Antenatal syphilis screening | Syphilis treatment (in pregnant women found positive) | Perinatal costs (for all pregnancies) | ||
| Existing: single screen | ||||
| Estimate | £1 777 469 008 | £9 697 904 | £535 434 | £1 767 235 670 |
| Lower 95% CI Upper 95% CI | £1 769 393 140 £1 778 772 048 | £9 661 636 £9 822 870 | £532 820 £545 591 | £1 759 111 560 £1 768 490 710 |
| Alternative: repeat screen | ||||
| Estimate | £1 787 355 870 | £18 860 259 | £970 254 | £1 767 525 357 |
| Lower 95% CI Upper 95% CI | £1 779 322 118 £1 788 703 813 | £18 786 836 £19 100 346 | £964 636 £989 342 | £1 759 402 583 £1 768 782 187 |
| Cost difference | £9 886 863 | £9 162 355 | £434 820 | £289 687 |
*Costs to the NHS in the UK for all 725 891 pregnant women screened. Costs are spilt into (1) antenatal screening costs, which includes sample collection and laboratory testing; (2) syphilis treatment within sexual health clinics and (3) perinatal costs, which includes the costs of delivery and neonatal care for all infants.
NHS, National Health Service.