MEDLINE search (Ovid interface)
| # | Searches | Results |
| 1 | exp Diabetes Mellitus, Type 1/ | 75 008 |
| 2 | (((autoimmune$ or insulin-dependent$ or insulindependent$ or juvenile$ or type-1 or type-i) adj3 diabet$) or dm1 or iddm$ or t1d? or td1).ti,ab,kw,kf. | 83 666 |
| 3 | or/1–2 | 109 351 |
| 4 | ((add-on$ or addon$ or adjunct$) adj3 (therap$ or treatment$)).ti,ab,kw,kf. | 29 534 |
| 5 | Hypoglycemic Agents/ | 63 885 |
| 6 | (anti-diabetic$ or antidiabetic$ or anti-hyperglyc?emic$ or antihyperglyc?emic$ or hypoglyc?emic$).ti,ab,kw,kf. | 48 317 |
| 7 | or/5–6 | 90 420 |
| 8 | exp alpha-Glucosidases/ | 4578 |
| 9 | ((alpha-glucosidas$ or alphaglucosidas$) adj3 inhibit$).ti,ab,kw,kf. | 3925 |
| 10 | Acarbose/ | 1329 |
| 11 | (acarbose$ or bay-g-5421$ or bay-g5421$ or bayg-5421$ or bayg5421$ or glucobay$ or glucor$ or glumida$ or prandase$ or precise$).ti,ab,kw,kf. | 233 207 |
| 12 | (voglibos$ or basen$).ti,ab,kw,kf. | 492 |
| 13 | or/10–12 | 233 830 |
| 14 | exp Amylin Receptor Agonists/ | 2438 |
| 15 | amylin$.ti,ab,kw,kf. | 2086 |
| 16 | (pramlintid$ or ac-?137$ or ac?137$ or symlin$).ti,ab,kw,kf. | 389 |
| 17 | or/14–16 | 3277 |
| 18 | Biguanides/ | 3189 |
| 19 | biguanid$.ti,ab,kw,kf. | 3071 |
| 20 | exp Buformin/ | 154 |
| 21 | (buformin$ or butylbiguanid$ or adebit$ or gliporal$ or silubin$).ti,ab,kw,kf. | 266 |
| 22 | exp Metformin/ | 13 011 |
| 23 | (metformin$ or dimethyl$guanidin$ or glucophage$).ti,ab,kw,kf. | 19 940 |
| 24 | exp Phenformin/ | 1474 |
| 25 | (phenformin$ or fenformin$ or phenylethylbiguanide$).ti,ab,kw,kf. | 1193 |
| 26 | or/18–25 | 26 861 |
| 27 | exp Colesevelam Hydrochloride/ | 199 |
| 28 | (c?olesevelam$ or gt-31104$ or gt31-104$ or gt31104$ or c?olestagel$ or welc?ol$).ti,ab,kw,kf. | 267 |
| 29 | or/27–28 | 302 |
| 30 | exp Bromocriptine/ | 6950 |
| 31 | (bromo#r#ptin$ or bromoergocr#ptin$ or cb-154$ or cb154$ or parlodel$).ti,ab,kw,kf. | 7735 |
| 32 | or/30–31 | 9362 |
| 33 | exp Dipeptidyl-Peptidase IV Inhibitors/ | 4661 |
| 34 | (((dipeptidyl-peptidase$ or dipeptidylpeptidase$ or dpp$) adj3 inhibit$) or gemigliptin$ or gliptin$ or lc15-0444$ or lc150444$).ti,ab,kw,kf. | 6931 |
| 35 | (alogliptin$ or syr-322$ or syr322$ or incresync$ or nesina$ or vipdomet$ or vipidia$).ti,ab,kw,kf. | 469 |
| 36 | (anagliptin$ or suiny$).ti,ab,kw,kf. | 79 |
| 37 | dutogliptin$.ti,ab,kw,kf. | 15 |
| 38 | (evogliptin$ or da-1229$ or da1229$ or suganon$).ti,ab,kw,kf. | 36 |
| 39 | (gosogliptin$ or pf-??734200$ or pf??734200$ or satrx$).ti,ab,kw,kf. | 11 |
| 40 | exp Linagliptin/ | 396 |
| 41 | (linagliptin$ or bi-1356$ or bi1356$ or jentadueto$ or tra?jenta$).ti,ab,kw,kf. | 722 |
| 42 | (omarigliptin$ or mk-3102$ or mk3102$ or marizev$).ti,ab,kw,kf. | 46 |
| 43 | (saxagliptin$ or bms-477118$ or bms477118$ or komboglyze$ or onglyza$ or qtern$).ti,ab,kw,kf. | 676 |
| 44 | exp Sitagliptin Phosphate/ | 1353 |
| 45 | (sitagliptin$ or mk-0431$ or mk0431$ or efficib$ or janumet$ or januvia$ or ristaben$ or ristfor$ or tesavel$ or velmetia$ or xelevia$).ti,ab,kw,kf. | 2271 |
| 46 | (teneligliptin$ or tenelia$).ti,ab,kw,kf. | 146 |
| 47 | (trelagliptin$ or syr-472$ or syr472$ or zafatek$).ti,ab,kw,kf. | 43 |
| 48 | exp Vildagliptin/ | 621 |
| 49 | (vildagliptin$ or nvp-laf237$ or nvplaf237$ or eucreas$ or galvus$ or icandra$ or jalra$ or xiliarx$ or zomarist$).ti,ab,kw,kf. | 1011 |
| 50 | or/33–49 | 9018 |
| 51 | exp Gastric Inhibitory Polypeptide/ | 2513 |
| 52 | ((gastric$ adj3 inhibit$ adj3 polypeptid$) or ((glucose-dependent$ or glucosedependent$) adj3 (insulin-releas$ or insulinreleas$ or insulintropic$) adj3 (polypeptide$ or peptide$)) or gip).ti,ab,kw,kf. | 3852 |
| 53 | (tirzepatid$ or ly-3298176$ or ly3298176$).ti,ab,kw,kf. | 3 |
| 54 | or/51–53 | 4368 |
| 55 | exp Glucagon-Like Peptide 1/ | 8398 |
| 56 | exp Glucagon-Like Peptide-1 Receptor/ | 2789 |
| 57 | (glp-1$ or glp1$ or ((glucagon-like or glucagonlike) adj3 peptid$)).ti,ab,kw,kf. | 15 628 |
| 58 | (albiglutid$ or eperzan$ or tanzeum$).ti,ab,kw,kf. | 193 |
| 59 | (dulaglutid$ or ly-2189265$ or ly2189265$ or trulicity$).ti,ab,kw,kf. | 350 |
| 60 | Exenatide/ | 2364 |
| 61 | (exenatid$ or ac-2993$ or ac2993$ or itca-650$ or itca650$ or exendin-4$ or (ex4 adj1 peptid$) or bydureon$ or byetta$).ti,ab,kw,kf. | 3358 |
| 62 | Liraglutide/ | 1597 |
| 63 | (liraglutid$ or nn-2211$ or nn2211$ or saxenda$ or victoza$ or xultophy$).ti,ab,kw,kf. | 2621 |
| 64 | (lixisenatid$ or aqve-10010$ or aqve10010$ or ave-?010$ or ave?010$ or zp-10$ or zp10$ or adlyxin$ or lyxumia$ or suliqua$).ti,ab,kw,kf. | 444 |
| 65 | (semaglutid$ or nn-9535$ or nn9535$ or ozempic$).ti,ab,kw,kf. | 335 |
| 66 | (taspoglutid$ or itm-077 or itm077$).ti,ab,kw,kf. | 59 |
| 67 | or/55–66 | 18 473 |
| 68 | (meglitinid$ or glinitid$ or hb-699$ or hb699$).ti,ab,kw,kf. | 327 |
| 69 | (miglitol$ or bay-m-1099? or bay-m1099? or baym-1099? or baym1099? or glyset? or diastabol$ or plumarol$).ti,ab,kw,kf. | 318 |
| 70 | (mitiglinid$ or miti-glinid$ or kad-1229$ or kad1229$ or s-21403$ or s21403$).ti,ab,kw,kf. | 144 |
| 71 | exp Nateglinide/ | 389 |
| 72 | (nateglinid$ or nate-glinid$ or senaglinid$ or a?−4166$ or a?4166$ or djn-608$ or djn608$ or fastic$ or starlix$ or starsis$ or trazec$).ti,ab,kw,kf. | 665 |
| 73 | (repaglinid$ or repa-glinid$ or ag-ee-388$ or ag-ee388$ or agee388$ or ag-ee-623$ or ag-ee623$ or ag-ee623$ or enyglid$ or gluconorm$ or prandin$ or novonorm$).ti,ab,kw,kf. | 764 |
| 74 | or/68–73 | 1975 |
| 75 | exp Sodium-Glucose Transporter 2 Inhibitors/ | 2143 |
| 76 | (((sodium-glucose$ or sodiumglucose$) adj3 (transporter$ or co-transporter$ or cotransporter$)) or sglt$ or gliflozin$).ti,ab,kw,kf. | 5883 |
| 77 | exp Canagliflozin/ | 583 |
| 78 | (canagliflozin$ or ta-7284$ or ta7284$ or invokana$ or vokanamet$).ti,ab,kw,kf. | 986 |
| 79 | (dapagliflozin$ or bms-512148$ or bms512148$ or ebymect$ or edistride$ or forxiga$ or xigduo$).ti,ab,kw,kf. | 1086 |
| 80 | (empagliflozin$ or bi-10773$ or bi10773$ or glyxambi$ or jardiance$ or synjardy$).ti,ab,kw,kf. | 1147 |
| 81 | (ertugliflozin$ or pf-04971729$ or pf04971729$ or steglatro$ or steglujan$ or segluromet$).ti,ab,kw,kf. | 98 |
| 82 | (ipragliflozin$ or asp-1941$ or asp1941$ or suglat$).ti,ab,kw,kf. | 205 |
| 83 | licogliflozin$.ti,ab,kw,kf. | 4 |
| 84 | (luseogliflozin$ or ts-071$ or ts071$ or lusefi$).ti,ab,kw,kf. | 102 |
| 85 | remogliflozin$.ti,ab,kw,kf. | 25 |
| 86 | sergliflozin$.ti,ab,kw,kf. | 15 |
| 87 | (sotagliflozin$ or lx-4211$ or lx4211$ or zynquista$).ti,ab,kw,kf. | 66 |
| 88 | (tofogliflozin$ or csg-452$ or csg452$ or apleway$ or deberza$).ti,ab,kw,kf. | 107 |
| 89 | or/75–88 | 6739 |
| 90 | exp Somatostatin/ | 19 052 |
| 91 | (somatostatin$ or (somatotropin$ adj3 (factor$ or hormone$)) or srih-14$ or srih14$ or somatofalk$ or stilamin$).ti,ab,kw,kf. | 30 432 |
| 92 | exp Octreotide/ | 7507 |
| 93 | (octreotid$ or compound-201–995$ or compound-201995$ or compound201-995$ or compound 201995$ or san$−201–995$ or san$−201995$ or san$201–995$ or san$201995$ or sm?−201–995$ or sm?−201995$ or sm?201–995$ or sm?201995$ or sandostatin$).ti,ab,kw,kf. | 8680 |
| 94 | or/90–93 | 38 435 |
| 95 | exp Sulfonylurea Compounds/ | 18 994 |
| 96 | sulfonylurea$.ti,ab,kw,kf. | 7883 |
| 97 | Acetohexamide/ | 238 |
| 98 | (acetohexamid$ or d#melor$ or gamadiabet$).ti,ab,kw,kf. | 203 |
| 99 | Carbutamide/ | 532 |
| 100 | (aminophenurobutan$ or bu#arban$ or butylcarbamid$ or diabetal$ or glucidoral$ or glybutamid$ or oran#l$ or sulfaninylbutylurea$).ti,ab,kw,kf. | 92 |
| 101 | Chlorpropamide/ | 1819 |
| 102 | (c?lorpropamid$ or diabinese$ or glucamid$ or insogen$ or meldian$).ti,ab,kw,kf. | 1504 |
| 103 | (glibornurid$ or ro-6–4563$ or ro6-4563$ or ro-64563$ or ro64563$ or gluborid$ or glutril$).ti,ab,kw,kf. | 95 |
| 104 | Gliclazide/ | 884 |
| 105 | (gl##lazid$ or s-1702$ or s1702$ or s-852$ or s852$ or diabrezid$ or diaglyk$ or diamicron$ or diaikron$ or diabrezid$ or glyade$).ti,ab,kw,kf. | 1394 |
| 106 | (gl#mepirid$ or hoe-490$ or hoe490$ or amar#l$ or roname$).ti,ab,kw,kf. | 2446 |
| 107 | Glipizide/ | 731 |
| 108 | (gl#pizid$ or k-4024$ or k4024$ or glucotrol$ or gl#diazinamid$ or glupitel$ or melizide$ or min?diab$ or ozidia$).ti,ab,kw,kf. | 1077 |
| 109 | (gl###idon$ or ar-df-26$ or ardf-26$ or ar-df26$ or ardf26$ or beglynor$ or glurenor$).ti,ab,kw,kf. | 179 |
| 110 | Glyburide/ | 6168 |
| 111 | (glyburid$ or hb-419$ or hb419$ or hb-420$ or hb420$ or daonil$ or diabeta$ or euglucon$ or gl#benclamid$ or maninil$ or micronase$ or neogluconin$).ti,ab,kw,kf. | 10 267 |
| 112 | Tolazamide/ | 168 |
| 113 | (tolazamid$ or norglycin$ or tol#nase$).ti,ab,kw,kf. | 169 |
| 114 | Tolbutamide/ | 5250 |
| 115 | (tolbutamid$ or artosin$ or diabetol$ or diaval$ or dolipol$ or orabet$ or orinase$ or rastinon$).ti,ab,kw,kf. | 7043 |
| 116 | or/95–115 | 32 466 |
| 117 | exp Thiazolidinediones/ | 11 549 |
| 118 | (thiazolidinedion$ or glitazon$).ti,ab,kw,kf. | 6432 |
| 119 | (pioglitazon$ or u-72107a$ or u72107a$ or ad-4833$ or ad4833$ or actos$ or competact$ or glidipion$ or glubrava$ or glustin$ or paglitaz$ or sepioglin$ or tandemact$).ti,ab,kw,kf. | 5431 |
| 120 | (rosiglitazon$ or brl-49653$ or brl49653$ or avaglim$ or avandamet$ or avandia$ or nyracta$ or venvia$).ti,ab,kw,kf. | 5807 |
| 121 | (troglitazon$ or cs-045$ or cs045$ or prelay$ or rezulin$).ti,ab,kw,kf. | 2348 |
| 122 | or/117–121 | 17 693 |
| 123 | exp Topiramate/ | 2715 |
| 124 | (topiramat$ or mcn-4853? or mcn4853? or usl-255? or usl255? or epitomax$ or topamax$).ti,ab,kw,kf. | 4608 |
| 125 | or/123–124 | 4936 |
| 126 | or/4–125 | 465 776 |
| 127 | (“randomized controlled trial” or “controlled clinical trial”).pt. | 591 452 |
| 128 | (groups or placebo or randomi#ed or randomly or trial).ab. | 2 807 236 |
| 129 | “drug therapy”.fs. | 2 190 159 |
| 130 | Cross-Over Studies/ | 47 393 |
| 131 | (cross-over or crossover).ti,ab,kw,kf. | 84 179 |
| 132 | or/127–131 | 4 706 281 |
| 133 | exp Animals/ not Humans/ | 4 683 296 |
| 134 | 132 not 133 | 4 081 128 |
| 135 | and/3,126,134 | 9978 |