Table 1

Baseline demographic and clinical characteristics of 226 patients with recurrent depression receiving mindfulness-based cognitive therapy who subsequently engaged in full, partial or no discontinuation of maintenance antidepressant medication (mADM) (adapted from Huijbers et al, 2016)

VariableTotal N=226*Sig.
Full discontinuation (n=110)Partial discontinuation (n=34)No discontinuation (n=82)
N%N%N%P value
Educational level0.421
Marital status0.560
Employed (n=225)6378226562560.009
 Full, IDS-C ≤11516217505045
 Partial, IDS-C >11313817506055
Type of mADM0.669
Previous CBT treatment4555216268620.595
Suicide attempt (lifetime)1822121521490.429
Age (years)
Baseline depression (IDS-C)10.98.812.711.214.410.60.059
Nr. previous episodes5.
Age at MDD onset (n=219)2711.92510.825.012.30.388
  • *Excluding 23 of the original 249 trial participants due to missing data regarding discontinuation.

  • †Including serotonin-norepinephrine reuptake inhibitors, monoamine oxidase-inhibitors and mirtazapine.

  • CBT, cognitive behavioural therapy; IDS-C, Inventory of Depressive Symptomatology-clinician rated; MDD, major depressive disorder; SSRI, selective serotonin reuptake inhibitor; TCA, tricyclic antidepressant.