Table 1

Baseline demographic and clinical characteristics of 226 patients with recurrent depression receiving mindfulness-based cognitive therapy who subsequently engaged in full, partial or no discontinuation of maintenance antidepressant medication (mADM) (adapted from Huijbers et al, 2016)

VariableTotal N=226*Sig.
Full discontinuation (n=110)Partial discontinuation (n=34)No discontinuation (n=82)
N%N%N%P value
Female6276185371640.048
Educational level0.421
 Low793966
 Middle242910293128
 High496021626458
 Missing220098
Marital status0.560
 Single19236182725
 Married/cohabiting465622656055
 Divorced/widowed15186181615
 Missing220076
Employed (n=225)6378226562560.009
Remission0.069
 Full, IDS-C ≤11516217505045
 Partial, IDS-C >11313817506055
Type of mADM0.669
 SSRI647823682119
 TCA13167212119
 Other†5641266
Previous CBT treatment4555216268620.595
Suicide attempt (lifetime)1822121521490.429
MeanSDMeanSDMeanSD
Age (years)50.011.152.09.851.010.30.507
Baseline depression (IDS-C)10.98.812.711.214.410.60.059
Nr. previous episodes5.64.97.48.05.73.90.167
Age at MDD onset (n=219)2711.92510.825.012.30.388
  • *Excluding 23 of the original 249 trial participants due to missing data regarding discontinuation.

  • †Including serotonin-norepinephrine reuptake inhibitors, monoamine oxidase-inhibitors and mirtazapine.

  • CBT, cognitive behavioural therapy; IDS-C, Inventory of Depressive Symptomatology-clinician rated; MDD, major depressive disorder; SSRI, selective serotonin reuptake inhibitor; TCA, tricyclic antidepressant.