Flow chart of the study showing timing collection of different variables
| Follow-up | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
| Months | 0 | 3 | 6 | 9 | 12 | 15 | 18 | 21 | 24 |
| Informed consent | x | ||||||||
| Medical history | x | ||||||||
| Physical examination | x | x | x | x | x | x | x | x | x |
| Serum 25-hydroxyvitamin D3 | x | x | x | x | x | x | x | x | x |
| Urine pregnancy test | x | x | x | x | x | x | x | x | x |
| Gynecologic ultrasound | x | x | x | x | x | x | x | x | x |
| Hepatic and renal function | x | x | x | x | x | ||||
| Electrolyte | x | x | x | x | x | ||||
| Blood routine examination | x | x | x | x | x | ||||
| Liver and urinary system ultrasound | x | x | x | ||||||
| Side effect assessment | x | x | x | x | x | x | x | x | |
| Changes in menstruation | x | x | x | x | x | x | x | x | |
| Adverse event assessment | x | x | x | x | x | x | x | x | |
| Vitamin D receptor genotype | x |