Table 2

Characteristics of the 2013 PCE validation cohort

CharacteristicTotal (n=810)Men (n=378)Women (n=432)P value*
Age (years), mean (SD)56.9 (10.0)57.9 (10.2)56.0 (9.6)0.006
Males, n (%)378 (46.7)
Smoking history, n (%)133 (16.4)126 (33.3)7 (1.6)<0.001
Diabetes mellitus, n (%)436 (53.8)224 (59.3)212 (49.1)0.004
Antihypertensive medication, n (%)522 (64.4)256 (67.7)266 (61.6)0.077
Lipid-lowering medication, n (%)500 (61.7)236 (62.4)264 (61.1)0.718
Body mass index (kg/m2), mean (SD)30.8 (6.5)29.1 (5.5)32.3 (6.9)<0.001
Systolic blood pressure (mm Hg), mean (SD)133.2 (18.1)134.8 (17.5)131.7 (18.5)0.016
Total cholesterol (mmol/L), mean (SD)5.04 (1.13)4.93 (1.13)5.15 (1.12)0.006
HDL-C (mmol/L), mean (SD)1.14 (0.32)1.03 (0.27)1.23 (0.34)<0.001
10 year PCE risk (%), median (25th, 75th percentile)8.7 (3.4 to 21.7)19.1 (8.2 to 31.6)4.6 (2.1 to 11.2)<0.001
10 year PCE risk ≥7.5%, n (%)442 (54.6)291 (77.0)151 (35.0)<0.001
Observed ASCVD events, n (%)102 (12.6)61 (16.1)41 (9.5)
Incidence rate, ASCVD cases/1000 person-years14.419.610.3
  • *The p values were calculated using the independent samples t-test for continuous variables and Fisher’s exact test (two tailed) for categorical variables. The Mann-Whitney U test was used to compare the median values of the 10 years PCE risk.

  • ASCVD, arteriosclerotic cardiovascular disease; HDL-C, high-density lipoprotein-cholesterol; PCE, Pooled Cohort Risk Equation.;