Characteristic | Total (n=810) | Men (n=378) | Women (n=432) | P value* |

Age (years), mean (SD) | 56.9 (10.0) | 57.9 (10.2) | 56.0 (9.6) | 0.006 |

Males, n (%) | 378 (46.7) | − | − | − |

Smoking history, n (%) | 133 (16.4) | 126 (33.3) | 7 (1.6) | <0.001 |

Diabetes mellitus, n (%) | 436 (53.8) | 224 (59.3) | 212 (49.1) | 0.004 |

Antihypertensive medication, n (%) | 522 (64.4) | 256 (67.7) | 266 (61.6) | 0.077 |

Lipid-lowering medication, n (%) | 500 (61.7) | 236 (62.4) | 264 (61.1) | 0.718 |

Body mass index (kg/m^{2}), mean (SD) | 30.8 (6.5) | 29.1 (5.5) | 32.3 (6.9) | <0.001 |

Systolic blood pressure (mm Hg), mean (SD) | 133.2 (18.1) | 134.8 (17.5) | 131.7 (18.5) | 0.016 |

Total cholesterol (mmol/L), mean (SD) | 5.04 (1.13) | 4.93 (1.13) | 5.15 (1.12) | 0.006 |

HDL-C (mmol/L), mean (SD) | 1.14 (0.32) | 1.03 (0.27) | 1.23 (0.34) | <0.001 |

10 year PCE risk (%), median (25th, 75th percentile) | 8.7 (3.4 to 21.7) | 19.1 (8.2 to 31.6) | 4.6 (2.1 to 11.2) | <0.001 |

10 year PCE risk ≥7.5%, n (%) | 442 (54.6) | 291 (77.0) | 151 (35.0) | <0.001 |

Observed ASCVD events, n (%) | 102 (12.6) | 61 (16.1) | 41 (9.5) | |

Incidence rate, ASCVD cases/1000 person-years | 14.4 | 19.6 | 10.3 |

*The p values were calculated using the independent samples t-test for continuous variables and Fisher’s exact test (two tailed) for categorical variables. The Mann-Whitney U test was used to compare the median values of the 10 years PCE risk.

ASCVD, arteriosclerotic cardiovascular disease; HDL-C, high-density lipoprotein-cholesterol; PCE, Pooled Cohort Risk Equation.;