Difference in QALY for intervention and control buildings
| Intervention building residents vs control building residents | |||
| Intervention mean (SD) | Control mean (SD) | Mean difference (95% CI) | |
| Main trial results with multiple imputation (intention-to-treat) | n=358 | n=320 | |
| Adjusted* QALY: QALY, regression adjusted for baseline utility score and building pairing | 0.72 (0.11) | 0.69 (0.20) | 0.03† (0.01 to 0.05) |
| Bootstrapping without multiple imputation (complete case) | n=196 | n=125 | |
| Adjusted* QALY: QALY, regression adjusted for baseline utility score and building pairing | 0.72 (0.09) | 0.69 (0.09) | 0.03† (0.01 to 0.05) |
| Bootstrap probabilistic sensitivity analysis: adjusted* QALY (QALY, regression adjusted for baseline utility score and building pairing) | 0.74 (0.09) | 0.71 (0.09) | 0.03† (0.01 to 0.05) |
*Intervention and control EQ-5D index scores were found to be significantly different at baseline, despite randomisation, therefore baseline differences were accounted for by adjustment using regression.
†p<0.05.
QALY, quality-adjusted life year.