Table 3

Development and final coefficients for the male and female prognostic models

PredictorMaleFemale
Development modelFinal modelDevelopment modelFinal model
Coefficient95% CIP valueCoefficientCoefficient95% CIP valueCoefficient
HbA1c (mmol/mol)0.350480.33231–0.368660.0000.341240.384940.36673–0.403150.0000.38255
Age−0.00310−0.00579 – −0.000400.024−0.00302−0.00465−0.00737 – −0.001930.001−0.00462
Current alcohol user0.05866−0.00659–0.123910.0780.057110.03588−0.03874–0.110500.3460.03566
Current smoker−0.13053−0.21393 – −0.047140.002−0.12709−0.11355−0.20407 – −0.023020.014−0.11284
Antihypertensive0.13787−0.03490–0.310640.1180.134230.23830−0.01509–0.491690.0650.23682
Aspirin0.109170.04131–0.177030.0020.106290.130780.06142–0.200150.0000.12997
Corticosteroids0.136830.07441–0.199260.0000.133220.125930.05951–0.192340.0000.12515
Statins0.651130.58046–0.721800.0000.633960.668860.60170–0.736030.0000.66471
Cardiovascular disease−0.08578−0.16955 – −0.002010.045−0.08352−0.11919−0.22249 – −0.015900.024−0.11845
Diabetes in family0.653790.10842–1.199170.0190.636550.37641−0.31827–1.071100.2880.37408
Polycystic ovarian syndrome0.22766−0.08223–0.537550.1500.22625
Gestational diabetes0.498650.24068–0.756610.0000.49555
Renal/kidney disease−0.05138−0.15758–0.054810.343−0.05003−0.13741−0.23253 – −0.042290.005−0.13655
Sleep apnoea0.08901−0.09730–0.275320.3490.086660.358320.04615–0.670480.0240.35609
Systolic blood pressure (mm Hg)0.005940.00383–0.008050.0000.005780.005990.00347–0.008520.0000.00596
Diastolic blood pressure (mm Hg)0.003590.00009–0.007080.0440.003490.00053−0.00333–0.004390.7840.00053
Restricted cubic spline 10.966610.94161–0.991600.0000.966610.930460.90612–0.954810.0000.93046
Restricted cubic spline 2−0.03565−0.05114 – −0.020160.000−0.03565−0.02957−0.04468 – 0.014450.000−0.02957
Restricted cubic spline 30.037080.02516–0.049010.0000.037080.019330.00740–0.031270.0020.01933
Constant−19.55409−20.40687 – −18.701310.000−19.55409−20.84774−21.70300 – −19.992470.000−20.84774
  • Final model coefficients include adjustment for over-fitting.