Measures completed by the child across project timepoints and according to child age group
| Child age group | Assessment time points | Variable role/analysis | Variable role/analysis | ||||||||
| 6–12 months | 12–24 months | >24 months | T0 pre | T1 ED | T2 10d | T3 1m | T4 3m | T5 1y | Aim 1 | Aim 3 | |
| Injury story | |||||||||||
| – | – | Injury story | o | Qualitative analyses | – | ||||||
| Global development | |||||||||||
| Brigance Early Childhood Screens III | Brigance Early Childhood Screens III | Brigance Early Childhood Screens III | o | Descriptive | – | ||||||
| Language (executive aspects) | |||||||||||
| – | – | NEPSY-II Speeded naming (36m+) | o | Outcome | Predictor* | ||||||
| – | – | NEPSY-II Word generation (36m+) | o | Outcome | Predictor | ||||||
| Executive functions | |||||||||||
| Global executive function | – | – | MEFS | o | o | Outcome | Predictor | ||||
| Inhibition | – | – | Bear and Dragon | o | o | Outcome | Predictor | ||||
| Working memory | – | Delayed Response | Picture memory (30m+) | o | o | Outcome | Predictor | ||||
| – | Stationary boxes | Stationary boxes | o | o | Outcome | Predictor | |||||
| Motor functions | |||||||||||
| Gross motor | Brigance Inventory of Early Development III | Brigance Inventory of Early Development III | Brigance Inventory of Early Development III | o | Outcome | Predictor | |||||
| Fine motor | Brigance Inventory of Early Development III | Brigance Inventory of Early Development III | Brigance Inventory of Early Development III | o | Outcome | Predictor | |||||
| Social cognition and competence | |||||||||||
| Joint attention | ESCS | ESCS | ESCS (36m-) | o | Outcome | Predictor | |||||
| Prosocial behaviour | – | Affective Response to Distress | Affective Response to Distress | o | Outcome | Predictor | |||||
| Emotion recognition | – | Emotion Discrimination Task | Emotion Discrimination Task | o | Outcome | Predictor | |||||
| Socio-emotional functioning | |||||||||||
| Temperament (frustration) | Lab-TAB - Attractive toy | Lab-TAB - Attractive toy | Lab-TAB - Attractive toy | o | Outcome | Predictor | |||||
| Pain | |||||||||||
| FLACC | FLACC | FLACC | o | Outcome | Predictor | ||||||
| – | – | Pain ratings | o | o | o | Outcome | Predictor | ||||
| Parent-child interactions | |||||||||||
| Quality of relationship | MRO (free-play) | MRO (free play and snack) | MRO (free play and snack) | o | o | o | Outcome | Predictor | |||
| SLEEP | |||||||||||
| Actigraphy | Actigraphy | Actigraphy | o | Outcome | Predictor | ||||||
| Brain structure and function | |||||||||||
| MRI (36m+) | o | Exploratory MRI analyses (Aim 2) | Predictor | ||||||||
| Pre- and post-injury stress | |||||||||||
| Hair cortisol | Hair cortisol | Hair cortisol | o | o | Outcome | Predictor | |||||
| Genetics (optional) | |||||||||||
| BDNF | Saliva | Saliva | Saliva | o | Exploratory genetics analyses | Predictor | |||||
*Predictors listed are potential candidates for inclusion in the predictive model and subject to the analysis plan to limit the number in the final model; Injury predictors include variables drawn from the case report form.
BDNF, Brain-derived neurotrophic factor; 10d, 10 days; ED, emergency department; ESCS, Early Social-Communication Scales; FLACC, Face Legs Activity Cry and Consolability; Lab-TAB, Laboratory Temperament Assessment Battery; 1m, 1 month; 3m, 3 months; MEFS, Minnesota Executive Function Scale; MRO, Mutually Responsive Orientation; MRO, Mutually Responsive Orientation; 1y, 1 year.