Cause of death among patients with ONS death registry linkage (n=109 966)
| Cause of death | Untested controls (n=22 069) | Normal inflammatory markers (n=61 390) | Raised inflammatory markers (n=26 507) | Comparison between normal and raised inflammatory markers | ||||
| No of deaths | 1-year mortality (%) | No of deaths | 1-year mortality (%) | No of deaths | 1-year mortality (%) | Unadjusted odds ratio (CI) | OR, adjusted for age and gender (CI) | |
| All-cause mortality | 380 | 1.74 | 889 | 1.45 | 1872 | 7.08 | 5.16 (4.76 to 5.60)* | 3.66 (3.37 to 3.99)* |
| Cancer | 86 | 0.39 | 195 | 0.32 | 696 | 2.63 | 8.46 (7.21 to 9.93) | 6.34 (5.40 to 7.46)* |
| Cardiovascular disease | 115 | 0.52 | 295 | 0.48 | 449 | 1.69 | 3.57 (3.08 to 4.14)* | 2.18 (1.87 to 2.54)* |
| Respiratory | 53 | 0.24 | 141 | 0.23 | 264 | 1 | 4.37 (3.56 to 5.36)* | 2.68 (2.18 to 3.30)* |
| Dementia | 38 | 0.17 | 69 | 0.11 | 119 | 0.45 | 4.01 (2.98 to 5.39)* | 2.21 (1.64 to 2.99)* |
| Gastrointestinal | 16 | 0.07 | 42 | 0.07 | 86 | 0.32 | 4.75 (3.29 to 6.88)* | 3.58 (2.46 to 5.20)* |
| Genitourinary | 8 | 0.04 | 16 | 0.03 | 39 | 0.15 | 5.65 (3.16 to 10.1)* | 3.13 (1.74 to 5.64)* |
| Infection | 5 | 0.02 | 11 | 0.02 | 29 | 0.11 | 6.11 (3.05 to 12.2)* | 4.08 (2.03 to 8.23)* |
| Blood disorder | 2 | 0.01 | 11 | 0.02 | 25 | 0.09 | 5.27 (2.59 to 10.7)* | 3.11 (1.52 to 6.37) |
| Senility | 12 | 0.05 | 8 | 0.01 | 21 | 0.08 | 6.08 (2.69 to 13.7)* | 2.80 (1.23 to 6.38) |
| Musculoskeletal | 3 | 0.01 | 8 | 0.01 | 14 | 0.05 | 4.05 (1.70 to 9.67)* | 2.40 (1.00 to 5.77) |
| Falls | 4 | 0.02 | 10 | 0.02 | 6 | 0.02 | 1.39 (0.51 to 3.82) | 0.80 (0.29 to 2.22) |
| Other | 38 | 0.17 | 83 | 0.14 | 124 | 0.47 | 3.47 (2.62 to 4.59)* | 2.41 (1.82 to 3.20)* |
*P<0.05.