Table 1

Gantt chart detailing trial procedures

ProcedurePhase 1Phase 2 (long-term follow-up)
ScreeningBaseline6 weeks3 months and every 6 months1st year2nd year3rd year4th year5th year
Eligibility assessmentXX
Informed consentX
Demographic data (DOB, sex, ethnicity, height and weight)X
Smoking and dietX
Relevant clinical history—especially determining arrhythmia aetiologyX
Evaluation of left ventricular systolic function via echocardiography, CMRI or radionucleotide imagingX
Record current medicationsX
Lying and standing BPX
Routine blood tests: U&E (sodium, potassium, urea and creatinine), GFR, glucose, and HbA1c
Vascular biomarkers: high-sensitivity troponin, NT-pro BNP, CRP, high-sensitivity CRP, interleukin-6
ICD implantationX
Routine ICD interrogationXXXXXXX
  • BNP, brain natriuretic peptide; BP, blood pressure; CMRI, cardiac MRI; CRP, C reactive protein; DOB, date of birth; GFR, glomerular filtration rate; hbA1c, haemoglobin A1c; ICD, implantable cardioverter defibrillator.