Basic characteristics of women with a live birth outcome (n=381) and subgroups of selected pregnancy-associated complications in the molecular signature in pregnancy cohort
| Overall (n=381) | Preterm (n=19) | GDM (n=50) | Anaemia (n=62) | Underweight (n=73) | SGA (n=77) | |
| Inclusion EGA (days); median (range) | 82 (56–97) | 83 (60–94) | 82.5 (56–97) | 81 (60–94) | 81 (57–95) | 81 (62–97) |
| Maternal age groups (years) | ||||||
| 18–24 | 185 (48.6) | 14 (73.7) | 25 (50.0) | 28 (45.2) | 43 (58.9) | 38 (49.4) |
| 25–29 | 95 (24.9) | 2 (10.5) | 12 (24.0) | 14 (22.6) | 18 (24.7) | 18 (23.4) |
| 30–34 | 64 (16.8) | 3 (15.8) | 8 (16.0) | 12 (19.4) | 10 (13.7) | 13 (16.9) |
| 35–39 | 25 (6.6) | 0 | 4 (8.0) | 5 (8.1) | 2 (2.7) | 6 (7.8) |
| 40–49 | 12 (3.1) | 0 | 1 (2.0) | 3 (4.8) | 0 | 2 (2.6) |
| Residence | ||||||
| Myanmar | 263 (69.0) | 10 (52.6) | 33 (66.0) | 42 (67.7) | 43 (58.9) | 52 (67.5) |
| Thailand | 118 (31.0) | 9 (47.4) | 17 (34.0) | 20 (32.3) | 18 (24.7) | 25 (32.5) |
| Gravidity | ||||||
| Primigravida | 103 (27.0) | 8 (42.1) | 12 (24.0) | 17 (27.4) | 32 (43.8) | 26 (33.8) |
| 2 | 111 (29.1) | 8 (42.1) | 16 (32.0) | 21 (33.9) | 21 (28.8) | 18 (23.4) |
| 3 | 79 (20.7) | 2 (10.5) | 12 (24.0) | 14 (22.6) | 9 (12.3) | 13 (16.9) |
| 4 | 47 (12.3) | 1 (5.3) | 7 (14.0) | 4 (6.5) | 8 (11.0) | 11 (14.3) |
| ≥5 | 41 (10.8) | 0 | 3 (6.0) | 6 (9.7) | 3 (4.1) | 9 (11.7) |
| Parity | ||||||
| 0 (nullipara) | 127 (33.3) | 9 (47.4) | 16 (32.0) | 23 (37.1) | 37 (50.7) | 32 (41.6) |
| 1 | 117 (30.7) | 8 (42.1) | 15 (30.0) | 18 (29.0) | 18 (24.7) | 16 (20.8) |
| 2 | 70 (18.4) | 1 (5.3) | 11 (22.0) | 14 (22.6) | 11 (15.1) | 13 (16.9) |
| 3 | 39 (10.2) | 1 (5.3) | 7 (14.0) | 2 (3.2) | 4 (5.5) | 11 (14.3) |
| ≥4 | 28 (7.3) | 0 | 1 (2.0) | 5 (8.1) | 3 (4.1) | 5 (6.5) |
| Literate | 244 (64.0) | 13 (68.4) | 29 (58.0) | 43 (69.4) | 53 (72.6) | 51 (66.2) |
| Smoking during in pregnancy | 29 (7.6) | 0 | 6 (12.0) | 5 (8.1) | 4 (5.5) | 10 (13.0) |
| Obstetric history* | ||||||
| Miscarriage | 94 (33.8) | 2 (18.2) | 11 (28.9) | 15 (33.3) | 13 (31.7) | 19 (37.3) |
| Stillbirth | 4 (1.4) | 0 | 0 | 1 (2.2) | 0 | 0 |
| PIH | 2 (0.7) | 0 | 0 | 1 (2.2) | 0 | 0 |
| Preterm rupture of membranes | 8 (2.9) | 2 (18.2) | 0 | 3 (6.7) | 1 (2.4) | 1 (2.0) |
| Preterm labour | 23 (8.3) | 6 (54.5) | 0 | 9 (20.0) | 3 (7.3) | 3 (5.9) |
| Vacuum delivery | 3 (1.1) | 0 | 0 | 1 (2.2) | 1 (2.4) | 0 |
| Postpartum haemorrhage | 9 (3.2) | 0 | 0 | 3 (6.7) | 2 (4.9) | 2 (3.9) |
| Retained placenta | 1 (0.4) | 0 | 0 | 0 | 0 | 0 |
| Previous neonatal death | 9 (3.2) | 3 (27.3) | 0 | 3 (6.7) | 0 | 1 (2.0) |
| History of GDM | 2 (0.7) | 0 | 2 (5.3) | 0 | 0 | 0 |
| Macrosomia | 2 (0.7) | 0 | 1 (2.6) | 0 | 0 | 0 |
Basic characteristics of pregnant women who completed per protocol follow-up with a live birth outcome, compared between various pregnancy-associated complications and adverse pregnancy outcomes. One study participant may be represented in multiple subgroups.
Data presented as proportion n (%) or median (range).
*Proportions calculated based on multigravida (n=278) as denominator.
EGA, estimated gestational age; GDM, gestational diabetes; PIH, pregnancy induced hypertension; SGA, born too small for gestational age.