Table 4

Risk factors for in-hospital mortality

Univariate analysisMultivariate analysis
HR (95% CI)P valueHR (95% CI)P value
Age >65 years5.76 (3.46 to 9.60)<0.00013.41 (2.00 to 5.78)<0.0001
Males1.58 (1.00 to 2.50)0.0491.17 (0.73 to 1.86)0.52
Exposure to ACE inhibitors1.68 (1.03 to 2.74)0.041.28 (0.77 to 2.13)0.34
Exposure to sartan0.91 (0.52 to 1.61)0.76
Exposure to ACE inhibitors or sartan1.33 (0.88 to 2.02)0.17
Cardiovascular disease2.49 (1.63 to 3.79)<0.00011.37 (0.88 to 2.13)0.16
PaO2/FiO2 ≤200 mm Hg6.68 (4.25 to 10.52)<0.00013.57 (2.20 to 5.77)<0.0001
Presence of hARF at admission15.08 (4.78 to 47.59)<0.0013.58 (1.05 to 12.18)0.04
CPAP at admission2.20 (1.32 to 3.67)0.0021.62 (0.96 to 2.72)0.07
  • Multivariate Cox regression analysis that identifies risk factors for in-hospital mortality. Data are reported as HR and 95% CIs.

  • ACEi, ACE inhibitor; CPAP, continuous positive airway pressure; FiO2, fraction of inhaled oxygen; PaO2, arterial partial pressure of oxygen.