Table 2

Cytokines and related indicators included in every study

AuthorCytokineReference testDiagnostic testTPFNFPTNCut-off value (pg/mL)
WonTNF-αIGRALuminex2115114373.6
IL-1023133120.145
WuIFN-γIGRALuminex13124321600
TNF-α20517191576
IL-22141521976.3
IL-102051521251
IP-1019612241139
JeongIFN-γTSTLuminex182825172.84
IP-1017333023 780
CliffordIFN-γTST and IGRALuminex3449341215
TNF-α2810439332
IP-10162243919 301
IL-2335835398
KimIFN-γTST and IGRAELISA208616None
IP-10280184None
TNF-α2711210None
WangIFN-γIGRALuminex181082677.6
IP-10131533110 821
IL-12151392557.39
VEGF1513331225.1
PathakumariIFN-γIGRAELISA831530116.4
TNF-α2118530381.8
IL-121524530171.4
HurTNF-αIGRAELISA3814922302.2
ZhangIFN-γIGRAFluoroSpot242936248
La MannaIFN-γIGRALuminex198329124
IP-10225527637
IL-222523090
IL-1215124286
YouIP-10IGRAELISA291112281587.76
IL-223171624106.51
IL-1034619210.18
SuzukawaTNF-αIGRALuminex1021227660.6
IP-10238141533 082
IL-2301227333.2
IL-1020113260.8
IL-12171462310.3
VEGF82322723.4
YaoIP-10IGRALuminex10101141580
VEGF17341137.54
WangIP-10IGRAELISA5974231451.3
IL-2579294413.1
  • FN, false negative; FP, false positive; IGRA, interferon-gamma release assay; TN, true negative; TP, true positive; TST, tuberculin skin test.