Dependent variable | Independent variable | Slope (95% CI) | P value |
Age | 0.09 (−0.11 to, 0.29) | 0.38 | |
BMI | −0.20 (−0.61 to 0.21) | 0.33 | |
Duration of surgery | 0.24 (−17.96 to 18.43) | 0.98 | |
Driving pressure | 0.63 (0.41 to 0.86) | <0.001* | |
Central venous pressure | Time points: | ||
T1 | Reference | ||
T2 | 11.52 (8.17 to 14.86) | <0.001* | |
T3 | 13.83 (9.99 to 17.67) | <0.001* | |
T4 | 14.09 (9.89 to 18.29) | <0.001* | |
T5 | 1.93 (−0.38 to 4.24) | 0.1 | |
Age | 0.003 (−0.02 to 0.02) | 0.77 | |
BMI | 0.01 (−0.03 to 0.05) | 0.67 | |
Duration of surgery | 1.89 (0.09 to 3.59) | 0.04* | |
Driving pressure | −0.01 (−0.03 to 0.01) | 0.52 | |
Noradrenalin | −0.52 (−2.01 to 0.98) | 0.5 | |
Cardiac Index | Time points: | ||
T1 | Reference | ||
T2 | 0.36 (0.05 to 0.66) | 0.022* | |
T3 | 0.54 (0.17 to 0.90) | 0.004* | |
T4 | 0.46 (0.06 to 0.86) | 0.025* | |
T5 | 0.66 (0.42 to 0.89) | <0.001* |
95% CI, BMI, T1: 20 min after induction of anaesthesia, T2: after insufflation of capnoperitoneum in supine position, T3: after 30 min in steep Trendelenburg position (STP), T4: when controlling Santorini’s plexus in STP, T5: after the laparoscopic procedure while in supine position before the end of anaesthesia; #patient-related, surgical-related, ventilatory and time-related confounders for multivariable analysis for haemodynamic parameter of cardiac preload and contractility.
*P<0.05.