Screening data for 2082 consecutive patients with laboratory-confirmed SARS-CoV-2 admitted to one of five centres
| RECOVERY | Combination* | C19-ACS | SIMPLE | Total | ||||
| Total screened per centre | 281 | 83 | 415 | Total (779) | 445 | 784 | 74 | 2082 |
| Number recruited (%) | 35 (12.5) | 16 (19.3) | 185 (44.6) | 236 (30.3) | 124 (27.9) | 56 (7.1) | 14 (18.9) | 430 (20.7) |
| Refused participation (%) | 10 (3.6) | 19 (22.9) | 16 (3.9) | 45 (5.8) | 8 (1.8) | 29 (3.7) | 0 (0.0) | 82 (3.9) |
| Clinical grounds/trial exclusion criteria(%) | 83 (29.5) | 15 (18.1) | 40 (9.6) | 138 (17.7) | 167 (37.5) | 365 (46.6) | 29 (39.2) | 699 (33.6) |
| Lacked capacity (%) | 22 (7.8) | 0 (0.0) | 1 (0.2) | 23 (3.0) | 16 (3.6) | 98 (12.5) | 0 (0.0) | 137 (6.6) |
| Mechanical ventilation (%) | 37 (13.2) | 7 (8.4) | 0 (0.0) | 44 (5.6) | 7 (1.6) | 48 (6.1) | 7 (9.5) | 106 (5.1) |
| Drug interactions (%) | 12 (4.3) | 2 (2.4) | 0 (0.0) | 14 (1.8) | 2 (0.4) | 1 (0.1) | 0 (0.0) | 17 (0.8) |
| Medically fit for discharge (%) | 55 (19.6) | 14 (16.9) | 77 (18.6) | 146 (18.7) | 65 (14.6) | 136 (17.3) | 16 (21.6) | 363 (17.4) |
| Palliative care (%) | 19 (6.8) | 7 (8.4) | 61 (14.7) | 87 (11.2) | 8 (1.8) | 51 (6.5) | 7 (9.5) | 153 (7.3) |
| Not approached or considered (%) | 8 (2.8) | 3 (3.6) | 35 (8.4) | 46 (5.9) | 48 (10.8) | 0 (0.0) | 1 (1.4) | 95 (4.6) |
| Total not recruited (%) | 246 (87.5) | 67 (80.7) | 230 (55.4) | 543 (69.7) | 321 (72.1) | 728 (92.9) | 60 (81.1) | 1652 (79.3) |
*Centre screened concurrently to both RECOVERY and SIMPLE: moderate and severe trials.