Table 2

Tests to be performed in each centre

Routine parametersFull blood count, fasting blood sugar, HbA1c, renal parameters, hepatic parameters, C reactive protein, protein electrophoresis, electrolytes including magnesium, lipid profile including high-/low-density lipoprotein -cholesterol
Bone-specific biomarkersOsteocalcin; carboxyl-terminal telopeptide of type I collagen; bone-specific alkaline phosphatase; tartrate-resistant acid phosphatase; N-propeptide of type I collagen; 25-hydroxyvitamin D; Intact parathyroid hormone
Hormones (optional—depending on indication)Follicle-stimulating hormone, Luteinising hormone, estradiol, testosterone
Genetic factorsSingle-nucleotide polymorphisms
Others (These parameters are only tested in Austria optionally and depending on the coverage of thecost)Fibroblast Growth Factor 23(FGF 23), Myostatin, Sclerostin