Table 1

The study eligibility criteria

Inclusion criteriaExclusion criteria

  • Age >18 years

  • Obstructive sleep apnoea syndrome (>15 respiratory micro awakenings per hour of sleep) with an indication for treatment

  • Recurring vasovagal syncope episodes defined as follows: at least three vasovagal syncopes during the last 2 years OR symptoms of orthostatic intolerance occurring in the last 6 months*

  • Pathology that may explain syncope symptoms

  • Cardiopathy

  • Known disautonomia

  • Hypotension of known origin

  • Adrenal insufficiency

  • Thyroid disorder

  • History of sudden death in a first degree family member

  • *Symptoms are triggered by orthostatism and can include presyncopes without loss of consciousness, asthenia, dizziness, visual disturbances, tinnitus, palpitations, headache, limitations of physical activity.