Table 1

Dosage of trial medication

Time pointMorningEvening
10 Preop. DaysP 20 mgP 20 mg
E 400 mgE 400 mg
Day of surgeryP 40 mgP 40 mg
E 400 mgE 400 mg
POD 1–7P 40 mgP 40 mg
E 400 mgE 400 mg
POD 8–14P 20 mgP 20 mg
E 400 mgE 400 mg
  • E, etodolac or corresponding placebo; P, propranolol or corresponding placebo; POD, postoperative day.