Outcome domains and measurement instruments | Time of measure | Type of quantity |
Sociodemographic variables | ||
Age | T0 | Continuous |
Sex | T0 | Binary |
Marital status, type of occupation, employment status, living situation | T0 | Categorical |
Medical variables | ||
Known IHD, hypertension, previous MI, PCI or CABG, chronic heart failure, diabetes mellitus, COPD and chronic kidney disease | T0 | Binary |
Clinical variables related to the cardiac arrest | ||
Place of OHCA, aetiology of cardiac arrest, initial rhythm, TTM, medication during ICU stay, LVEF | T0 | Categorical |
Bystander witnessed cardiac arrest, bystander performed CPR, use of AED, shockable rhythm, awake at arrival to hospital, TTM, intubated, medication during ICU, delirium at ICU | T0 | Binary |
Time to ROSC, intubation time, length of stay at ICU | T0 | Continuous |
Conscious state | ||
GCS | T0 | Categorical |
Neurological outcome | ||
CPC | T1 | Categorical |
Length of stay at hospital | T1 | Continuous |
Performance-based variables | ||
Delirium score | ||
4AT | T1 | Categorical |
Functional independence | ||
Barthel Index-20 | T1 | Categorical |
Cognitive status | ||
MoCA | T1 | Binary |
Brain activity while resting | ||
rsfMRI | T1 | Continuous |
Neuropsychological outcome | ||
VAMT-26, D- KEFS trail-taking, D-KEFS colour-word interference, D-KEFS design fluency, Rey’s complex figure and Letter-number sequencing: subtest of WAIS-IV | T2 | Binary |
Cortisol awakening response | T1 | Continuous |
Patient-reported outcome measures | ||
POMS | T1 | |
HADS, IES-R, CSS | T1, T2 | Continuous |
B-IPQ, FSS, HeartQoL, SF-12, PSQI, CISS, BRIEF-A, ECR-R, AMCQ, CES-S, MTEQ, PTGQ, ACQ, NDEQ | T2 | Continuous |
Lifestyle changes, health profile | T2 | Categorical |
Register based | ||
Depression, anxiety, dementia, chronical fatigue syndrome and heart failure, mortality and healthcare utilisation | T3 | Continuous |
ACQ, Attribution; AED, automated external defibrillator; AMCQ, Autobiographical Memory Characteristics Questionnaire; B-IPQ, Brief Illness Perception Scale; BRIEF-A, Behavior Rating Inventory of Executive Functions, adult version; CABG, coronary artery bypass surgery; CES-S, Centrality of Events–Short; CISS, Coping Inventory for Stressful Situations; COPD, chronic obstructive pulmonary disease; CPC, Cerebral Performance Category; CPR, cardiopulmonary resuscitation; CSS, Crisis Support Scale; D- KEFS, Delis–Kaplan Executive Function System; ECR-R, Experience in Close Relationships; FSS, Fatigue Severity Scale; GCS, Glasgow Coma Scale; HADS, Hospital Anxiety and Depression Scale; ICU, intensive care unit; IES-R, Impact of Event Scale-Revised; IHD, ischaemic heart disease; LVEF, left ventricular ejection fraction; MI, myocardial infarction; MoCA, Montreal Cognitive Assessment; MTEQ, Memory of Event Scale; NDEQ, Near-death Experience Questionnaire; OHCA, out-of-hospital cardiac arrest; PCI, percutaneous coronary intervention; POMS, Profile of Mood States; PSQI, Pittsburgh Sleep Quality Inventory; PTGQ, Post-Traumatic Growth Questionnaire; ROSC, return of spontaneous circulation; rsfMRI, resting state functional magnetic resonance imaging; SF-12, 12-item Short Form Survey; T0, pre-arrest, medical and clinical data; T1, during hospitalisation; T2, 3 months follow-up; T3, 1 year follow-up; TTM, targeted temperature management; VAMT-26, Danish Affective Verbal Learning Test-26.